An epidemic survey on freshwater puffer poisoning in Bangladesh.

Journal of natural toxins Pub Date : 2000-11-01
Y Mahmud, O Arakawa, T Noguchi
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Abstract

An epidemic investigation was carried out on freshwater puffer poisoning incidents in Bangladesh from April 1988 to May 1996. A lot of information on 10 poisoning cases involving 55 victims was collected through newspapers, interviewing the victims and their families, concerned hospital sources or questionnaires to them. Symptoms of the victims were partly similar to those caused by paralytic shellfish poison (PSP) or tetrodotoxin (TTX). Among them, however, muscle pain, discharge of black urine, and longer recovery time are clearly different. Further, serum creatine phosphokinase (CPK) values were found to be higher (230-450 and 298-430 IU/l) than normal values in two cases. From these different symptoms and high CPK values, it can be predicted/assumed that present freshwater puffer toxin is implicated in not only PSP, but also other toxin(s).

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孟加拉国淡水河豚中毒的流行病学调查。
1988年4月至1996年5月,对孟加拉国的淡水河豚中毒事件进行了流行病调查。通过报纸、对受害者及其家属的采访、有关医院来源或对他们进行问卷调查,收集了涉及55名受害者的10起中毒案件的大量信息。受害者的症状部分类似于麻痹性贝类中毒(PSP)或河豚毒素(TTX)引起的症状。但其中肌肉疼痛、排出黑尿、恢复时间较长有明显差异。此外,两例患者血清肌酸磷酸激酶(CPK)值高于正常值(230-450和298-430 IU/l)。根据这些不同的症状和较高的CPK值,可以预测/假设目前的淡水河豚毒素不仅与PSP有关,还与其他毒素有关。
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