Carcinoma in situ in the testis.

M Rørth, E Rajpert-De Meyts, L Andersson, K P Dieckmann, S D Fosså, K M Grigor, W F Hendry, H W Herr, L H Looijenga, J W Oosterhuis, N E Skakkebaek
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Abstract

Carcinoma in situ (CIS) of the testis is a common precursor of germ-cell tumours in adults and adolescents, with the exception of spermatocytic seminoma. This article reviews existing knowledge on the pathobiology, genetic aspects and epidemiology of CIS, discusses current hypotheses concerning pathogenesis and invasive progression of germ-cell neoplasms and provides guidelines for diagnosis and clinical management of CIS.

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睾丸原位癌。
除精原细胞瘤外,睾丸原位癌(CIS)是成人和青少年生殖细胞肿瘤的常见前兆。本文综述了CIS的病理生物学、遗传学和流行病学方面的现有知识,讨论了目前关于生殖细胞肿瘤的发病机制和侵袭进展的假设,并为CIS的诊断和临床治疗提供了指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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