Herbal remedy. Winning the malaria war.

Asiaweek Pub Date : 1994-05-18
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Abstract

The Chinese knew it all along. A reference to the healing power of qinghao is to be found in a list of "Prescriptions for 52 Kinds of Disease" written 2000 years ago. Now artemether, a derivative of the Chinese herb, has been proven the most effective tool in the fight against drug-resistant malaria. In a study of 97 severe cases conducted on the Thai-Cambodia border by Juntra Karbwang, artemether proved three times more effective than quinine. "Dr. Karbwang's study is of particular importance because it has been conducted in an area where the malaria parasite has become a monster, with resistance to most of the commonly used drugs," says Tore Godal, director of the UN tropical disease program. Used in Vietnam, a related herbal extract slashed malaria mortality rates by 80%. The drug will be manufactured in Kunming, China, and marketed by France's Rhone-Poulenc Rorer Doma. They needn't worry about demand, according to Nakajima Hiroshi. "In many countries malaria is worsening," says the World Health Organization director-general. "It kills some 1.5 to 3 million a year. The scientific demonstration of the success of this drug is a dramatic step forward for health."

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草药。赢得疟疾之战。
中国人一直都知道这一点。两千多年前的《五十二种病方》中就提到了青蒿的治疗功效。现在,中药的衍生物蒿甲醚已被证明是对抗抗药性疟疾的最有效工具。在一项由Juntra Karbwang在泰柬边境对97个严重病例进行的研究中,蒿甲醚被证明比奎宁有效三倍。联合国热带病项目主任Tore Godal说:“Karbwang博士的研究特别重要,因为它是在一个疟疾寄生虫已成为怪物的地区进行的,该寄生虫对大多数常用药物具有耐药性。”在越南,一种相关的草药提取物将疟疾死亡率降低了80%。该药将在中国昆明生产,并由法国罗纳-普朗克公司(Rhone-Poulenc Rorer Doma)销售。中岛浩表示,他们不需要担心需求。“在许多国家,疟疾正在恶化,”世界卫生组织总干事说。“它每年导致150万到300万人死亡。这种药物成功的科学证明是健康领域向前迈出的巨大一步。”
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