The effect of anesthetic techniques on hemostatic function in arthroscopic surgery: evaluation by thromboelastography.

Acta anaesthesiologica Sinica Pub Date : 2002-09-01
Go-Shine Huang, Jen-Huei Chang, Meei-Shyuan Lee, Chia-Chun Wu, Shu-Pi Lin, Shinn-Long Lin, Chih-Shung Wong
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Abstract

Background: Anesthetic techniques are known to affect blood hemostasis, which may be responsible for the pathogenesis of postoperative venous thromboembolism. The purpose of this study was to evaluate the effect of general and spinal anesthesias on blood hemostasis using thromboelastography.

Methods: Forty patients undergoing arthroscopic knee surgery were enrolled for study and randomly allocated to one of two groups, to receive either general (GA; n = 20) or spinal anesthesia (SA; n = 20). In addition to thromboelastography, prothrombin and activated partial-thromboplastin time, and haematocrit and platelet count were also examined concurrently. Blood was sampled and examined before anesthesia to provide the baseline data (Time 1). Three more evaluations were performed at different time, i.e., twenty minutes after induction of anesthesia and just prior to skin incision (Time 2), thirty minutes after skin incision (Time 3), and three hours after surgery (Time 4).

Results: There were no intra- or inter-group differences noted as comparing the measured parameters obtained prior to, during, or three hours after surgery.

Conclusions: From the present study, we do not find any individual anesthetic technique which would have effect on the hemostasis of patients who received diagnostic arthroscopic surgery.

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麻醉技术对关节镜手术止血功能的影响:血栓弹性成像评价。
背景:已知麻醉技术会影响血液止血,这可能是术后静脉血栓栓塞的发病机制。本研究的目的是评估全身麻醉和脊髓麻醉对血栓弹性成像止血的影响。方法:选取40例膝关节关节镜手术患者进行研究,随机分为两组,接受普通(GA)治疗;n = 20)或脊髓麻醉(SA;N = 20)。除了血栓弹性成像,凝血酶原和活化的部分凝血活酶时间,红细胞压积和血小板计数也被同时检查。麻醉前抽血并检查以提供基线数据(时间1)。在不同时间进行三次评估,即麻醉诱导后20分钟和皮肤切口前(时间2),皮肤切口后30分钟(时间3)和手术后3小时(时间4)。结果:与手术前,手术中或手术后3小时获得的测量参数相比,没有组内或组间差异。结论:从目前的研究来看,我们没有发现任何一种单独的麻醉技术对接受诊断性关节镜手术的患者的止血有影响。
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