[A patient with polymyalgia rheumatica who exhibited fever as the main symptom for a long period].

Ryumachi. [Rheumatism] Pub Date : 2002-10-01
Naoko Abe, Hayato Yamauchi, Takanori Senba, Naomi Torio, Reika Shimada, Takashi Yamane, Yasuhiko Imaizumi
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Abstract

We encountered a patient with polymyalgia rheumatica (PMR) who exhibited fever as the main symptom for a long period without muscular pain. As an etiological factor, the condition may have been associated with nonsteroidal anti-inflammatory drugs (NSAIDs). A 71-year-old man consulted our Department of Orthopedics for fever and lumbar pain, which initially developed in early September 2000. Administration of NSAIDs resulted in the disappearance of lumbar pain. However, fever persisted. The C-reactive protein (CRP) level was persistently high. Therefore, on October 5, 2000, the patient was referred to our department. At the outpatient clinic, a detailed examination was performed. However, the etiology could not be determined. Repeated administration of NSAIDs resulted in pyretolysis, and the dose of NSAIDs was decreased from January 31, 2001. Severe fever appeared again, and inflammatory reaction also exacerbated. On March 11, 2001, muscular pain involving the bilateral shoulders and forearms suddenly developed. For diagnostic treatment, administration of prednisolone (PSL) at 10 mg/day was started. Muscular pain rapidly disappeared. According to Bird's criteria, PMR was diagnosed. After the dose of PSL was decreased to 7.5 mg/day, the course is good. PMR should be considered as the etiology of idiopathic fever in elderly patients.

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[长时间以发热为主要症状的风湿病多肌痛患者]。
我们遇到了一个多肌痛风湿病(PMR)的病人,他表现出发烧为主要症状,长时间没有肌肉疼痛。作为一个病因因素,这种情况可能与非甾体抗炎药(NSAIDs)有关。一名71岁男性因发热和腰痛向我们骨科求诊,他最初于2000年9月初发病。给予非甾体抗炎药导致腰痛消失。然而,发烧仍在继续。c反应蛋白(CRP)持续升高。因此,在2000年10月5日,病人被转介到我科。在门诊进行了详细的检查。但病因不明。自2001年1月31日起,非甾体抗炎药的剂量减少。再次出现严重发热,炎症反应加重。2001年3月11日,双侧肩膀和前臂突然出现肌肉疼痛。对于诊断性治疗,开始使用强的松龙(PSL),剂量为10mg /天。肌肉疼痛迅速消失。根据伯德的诊断标准,确诊为PMR。PSL剂量降至7.5 mg/d后,病程良好。PMR应被视为老年患者特发性发热的病因。
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