Magdalena Modrzewska, Paweł Karpiński, Anna Grudniak, Krystyna I Wolska
{"title":"Effect of null mutations in dnaK and dnaJ genes on conjugational DNA transfer, proteolysis and novobiocin susceptibility of Escherichia coli.","authors":"Magdalena Modrzewska, Paweł Karpiński, Anna Grudniak, Krystyna I Wolska","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Escherichia coli null dnaJ and dnaKdnaJ mutants, when introduced to Hfr donor, impair its ability to DNA transfer during conjugation. The additive effect of both mutations was shown. Lack of DnaK and DnaJ chaperones also decrease the extent of proteolysis in mutant strains. This effect is seen only at 42 degrees C. The influence of double dnaKdnaJ deletion but not single dnaJ deletion on novobiocin susceptibility was also demonstrated.</p>","PeriodicalId":75388,"journal":{"name":"Acta microbiologica Polonica","volume":"51 3","pages":"217-24"},"PeriodicalIF":0.0000,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta microbiologica Polonica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Escherichia coli null dnaJ and dnaKdnaJ mutants, when introduced to Hfr donor, impair its ability to DNA transfer during conjugation. The additive effect of both mutations was shown. Lack of DnaK and DnaJ chaperones also decrease the extent of proteolysis in mutant strains. This effect is seen only at 42 degrees C. The influence of double dnaKdnaJ deletion but not single dnaJ deletion on novobiocin susceptibility was also demonstrated.
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