[Management of breast cancers diagnosed at the Pasteur Institute of Madagascar from 1995 to 2001].

C R Raharisolo Vololonantenaina, L P Rabarijaona, C Rajemiarimoelisoa, M Rasendramino, R Migliani
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Abstract

Breast cancer is a great problem of public health all over the world. In developed countries, breast cancer represents the most common cancer in females. Its incidence is also increasing in developing country. In Madagascar, no data is available to estimate the real incidence and prevalence rates of breast cancer. However, the data at the Institut Pasteur de Madagascar can confirm the extent of the problem even if it is not at a national scale. The authors report the results of a retrospective study from histological examination at the Laboratory of pathological anatomy of the IPM, during 7 years. Among 2,337 cases of cancer, 16% (373) were breast cancer. Most of them were a female breast cancer (356 cases). The average age is 48 years old. 30% of the tumors were more than 2 cm in size, corresponding at least to the T2 stade from the International Union Against Cancer anatomoclinical classification. The current histological type is the infiltrating ductal carcinoma (80%), about 2/3 belong to the grade 3 of the Scarff-Bloom-Richardson histopronostical classification. Early diagnosis of the cancer is difficult because of the insufficiency of the sanitary infrastructure, particularly for cervical and breast cancers. A national policy for screening must be set up in order to decrease the rate of these invasive carcinomas. In the meantime, informing women and training all the medical staff is a priority. Recording all the data in Madagascar would be desirable.

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[1995年至2001年在马达加斯加巴斯德研究所诊断的乳腺癌的管理]。
乳腺癌是全世界公共卫生的一大问题。在发达国家,乳腺癌是女性中最常见的癌症。其发病率在发展中国家也在增加。在马达加斯加,没有数据可用于估计乳腺癌的实际发病率和流行率。然而,马达加斯加巴斯德研究所的数据可以证实这个问题的严重程度,即使它不是在全国范围内。作者报告了在IPM病理解剖实验室进行的为期7年的组织学检查的回顾性研究结果。在2337例癌症中,16%(373例)为乳腺癌。其中大部分为女性乳腺癌(356例)。平均年龄为48岁。30%的肿瘤大小大于2cm,至少符合国际抗癌联盟解剖临床分型的T2期。目前组织学类型为浸润性导管癌(80%),约2/3属于Scarff-Bloom-Richardson组织学分级3级。由于卫生基础设施不足,特别是宫颈癌和乳腺癌的卫生基础设施不足,很难对癌症进行早期诊断。为了降低这些浸润性癌的发病率,必须制定一项全国性的筛查政策。与此同时,告知妇女和培训所有医务人员是一个优先事项。在马达加斯加记录所有的数据是可取的。
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