[Specific features of functional activity of neutrophilic granulocytes in infection with Mycobacterium tuberculosis in children of different age groups].

Abstract

Sixty children infected with Mycobacteria tuberculosis from two age groups (3-5 and 12-14 years) were followed up. The phagocytic activity and oxygen-dependent biocidicity of peripheral neutrophilic granulocytes were studied. The studies indicated dysfunctions of neutrophilic granulocytes in the children infected with Mycobacteria tuberculosis. This fact should be borne in mind in developing immunorehabilitative programmes in this category of patients. Moreover, the changes in the killing activity of neutrophilic turned out to be more pronounced in a young age group. In this connection, immunomodulating therapy should be strictly differentiated.