[Stability of immobilized insulin preparation at various pH].

Voprosy meditsinskoi khimii Pub Date : 2002-11-01
I L Valuev, G A Sytov, L I Valuev, L V Vanchugova, A V Pan, M V Ul'ianova, N A Platé
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引用次数: 0

Abstract

The stability of polyacrylamide hydrogel, modified by ovomucoid with immobilized insulin was studied at different pH of external medium. At 3.8 < pH < 5.5 insulin binds to the gel, due to electrostatic interaction between ovomucoid and insulin molecules.

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[固定化胰岛素制剂在不同pH值下的稳定性]。
研究了用固定化胰岛素修饰的卵泡样蛋白修饰的聚丙烯酰胺水凝胶在不同pH的外部介质下的稳定性。在3.8 < pH < 5.5时,由于卵黏液和胰岛素分子之间的静电相互作用,胰岛素与凝胶结合。
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