{"title":"Conformational changes in corticotropin solutions","authors":"C. Botré, M. Solinas","doi":"10.1016/0926-6577(64)90197-4","DOIUrl":null,"url":null,"abstract":"<div><p>The behaviour and physico-chemical characteristics of corticotropin, or adrenocorticotropic hormome (ACTH), in aqeous solution as a function of ionic strength and temperature have been studied. It is shown that sharp changes of physico-chemical properties of the solution take place when both temperature or ionic strength reach critical values. Such changes are discussed in terms of structural variations of the ACTH molecule.</p></div>","PeriodicalId":100169,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Biophysical Subjects","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1964-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6577(64)90197-4","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Biophysical Subjects","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0926657764901974","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
The behaviour and physico-chemical characteristics of corticotropin, or adrenocorticotropic hormome (ACTH), in aqeous solution as a function of ionic strength and temperature have been studied. It is shown that sharp changes of physico-chemical properties of the solution take place when both temperature or ionic strength reach critical values. Such changes are discussed in terms of structural variations of the ACTH molecule.
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