Dosimetry for an Sr90/Y90 source train used for intravascular radiation of a hemodialysis graft

Cardiovascular radiation medicine Pub Date : 2003-04-01 DOI:10.1016/S1522-1865(03)00164-1

Peter Bloch , Raoul Bonan , Paul Wallner , John Lobdell

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引用次数: 1

Abstract

Objective

Vascular access for hemodialysis is often achieved with an arterial–venous graft (AVG). Brachytherapy is being explored for prevention of stenosis within these grafts. The objective was to develop treatment planning (TP) capability for dialysis implants.

Material and methods

Fluoroscopic images are used to identify position of sources and irradiated vessel. An Sr⁹⁰/Y⁹⁰ beta source, jacketed in a CO₂-filled balloon, is used to irradiate the AVG. A single-seed Sr⁹⁰ dose kernel was generated using Monte Carlo. The single-seed dose kernel was employed to calculate the dose surrounding the implant accounting for the path length of the beta particles through the gas-filled balloon.

Results

Dose distributions are displayed superimposed on the fluoroscopic image of the AVG. Dose–area histograms were also generated.

Conclusion

TP for dialysis implants can be performed using radiographic localization of the graft. The TP tools could be used to correlate clinical outcome with dose delivery.

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用于血液透析移植物血管内辐射的Sr90/Y90源序列的剂量测定

目的通过动静脉移植(AVG)实现血液透析的血管通路。目前正在探索近距离治疗来预防这些移植物内的狭窄。目的是发展透析植入物的治疗计划(TP)能力。材料和方法荧光图像用于识别源和被照射容器的位置。一个Sr90/Y90 β源被包裹在一个充满二氧化碳的气球中，用来照射AVG。一个单种子Sr90剂量核是用蒙特卡罗生成的。采用单粒剂量核计算β粒子通过充气球囊的路径长度，计算植入物周围的剂量。结果在AVG透视图上叠加显示剂量分布，并生成剂量面积直方图。结论透析植入物的x线定位是可行的。TP工具可用于将临床结果与剂量给药相关联。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cardiovascular radiation medicine

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