[Celiac disease and autoimmune diseases or systemic disease. Six cases and a review of the literature].

Annales de medecine interne Pub Date : 2003-09-01

Xavier Delbrel, Patrick Le-Bougeant, Gabriel Etienne, Patrick Blanco, Marie Beylot-Barry, Michel Amouretti, Patrick Mercie, Maïté Longy-Boursier

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Abstract

Background: Celiac disease is an autoimmune disorder which may be associated with another autoimmune or systemic disease.

Objective: To determine the links between autoimmune diseases and celiac disease.

Patients and methods: Among 31 patients with a celiac disease, we selected those who had another autoimmune or systemic disease.

Results: We report 6 patients with such disease association: 3 with autoimmune thyroiditis including one also with Grave's disease, 2 with systemic lupus erythematosus including one also with insulin-dependent diabetes mellitus, and 1 with temporal arteritis.

Conclusion: The link between celiac disease and autoimmune thyroiditis or insulin-dependent diabetes mellitus seems to be real but many discrepancies are observed for the other autoimmune diseases. After a literature review, we suggest a summary of effective associations between celiac disease and autoimmune or systemic diseases.

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乳糜泻和自身免疫性疾病或全身性疾病六个病例和文献综述]。

背景:乳糜泻是一种自身免疫性疾病，可能与其他自身免疫性或全身性疾病相关。目的:探讨自身免疫性疾病与乳糜泻的关系。患者和方法:在31例患有乳糜泻的患者中，我们选择了那些患有其他自身免疫性或全身性疾病的患者。结果:我们报告了6例与该疾病相关的患者:3例合并自身免疫性甲状腺炎，1例合并格雷夫斯病，2例合并系统性红斑狼疮，1例合并胰岛素依赖性糖尿病，1例合并颞动脉炎。结论:乳糜泻与自身免疫性甲状腺炎或胰岛素依赖型糖尿病之间的联系似乎是真实的，但在其他自身免疫性疾病中观察到许多差异。在回顾文献后，我们建议总结乳糜泻与自身免疫性或全身性疾病之间的有效关联。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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