M Himaja, Rajiv, M V Ramana, Boja Poojary, D Satyanarayana, E V Subrahmanyam, K Ishwar Bhat
{"title":"Synthesis and biological activity of a novel series of 4-[2'-(6'-nitro)benzimidazolyl]benzoyl amino acids and peptides.","authors":"M Himaja, Rajiv, M V Ramana, Boja Poojary, D Satyanarayana, E V Subrahmanyam, K Ishwar Bhat","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>A series of new 4-[2'-(6'-nitro)benzimidazolyl]benzoyl amino acids and peptides have been synthesized by coupling the 4-[2'-(6'-nitro)benzimidazolyl]benzoic acid with amino acid methyl esters/dipeptides using DCC as the coupling agent. All the synthesized compounds were found to exhibit potent anthelmintic activity along with moderate antimicrobial activity.</p>","PeriodicalId":9085,"journal":{"name":"Bollettino chimico farmaceutico","volume":"142 10","pages":"450-3"},"PeriodicalIF":0.0000,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bollettino chimico farmaceutico","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A series of new 4-[2'-(6'-nitro)benzimidazolyl]benzoyl amino acids and peptides have been synthesized by coupling the 4-[2'-(6'-nitro)benzimidazolyl]benzoic acid with amino acid methyl esters/dipeptides using DCC as the coupling agent. All the synthesized compounds were found to exhibit potent anthelmintic activity along with moderate antimicrobial activity.
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