Quality of life intervention for prostate cancer patients: design and baseline characteristics of the active for life after cancer trial

Cindy L Carmack Taylor , Murray A Smith , Carl de Moor , Andrea L Dunn , Curtis Pettaway , Rena Sellin , Chuslip Charnsangavej , Molly C Hansen , Ellen R Gritz
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引用次数: 34

Abstract

Prostate cancer patients receiving androgen ablation therapy experience significant physical and psychological sequelae associated with their disease and treatment. Because physical activity improves physical and psychological well-being, a lifestyle physical activity intervention may help slow or reverse the associated decline in quality of life (QOL). No studies have evaluated an intervention to improve multiple QOL domains in patients receiving androgen ablation therapy. Active for Life After Cancer is a three-group randomized controlled trial designed to evaluate the effectiveness of a lifestyle physical activity intervention (Lifestyle Program) in improving QOL. The Lifestyle Program, a 6-month behavioral skills training group, is compared to an Educational Support Program and Standard Care. The purpose of this paper is to describe the design of the randomized trial and present baseline data that will characterize the QOL of the sample. Challenges to recruitment for the trial also will be presented and discussed.

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前列腺癌患者的生活质量干预:癌症后生活试验的设计和基线特征
前列腺癌患者接受雄激素消融治疗经历显著的生理和心理后遗症与他们的疾病和治疗。由于体育活动可以改善身心健康,生活方式体育活动干预可能有助于减缓或扭转相关的生活质量下降(QOL)。没有研究评估干预措施改善接受雄激素消融治疗的患者的多个生活质量域。癌症后积极生活是一项三组随机对照试验,旨在评估生活方式体育活动干预(生活方式计划)在改善生活质量方面的有效性。生活方式计划是一个为期6个月的行为技能训练组,与教育支持计划和标准护理进行比较。本文的目的是描述随机试验的设计,并提供基线数据,以表征样本的生活质量。还将介绍和讨论招募试验人员所面临的挑战。
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