What are production diseases, and how do we manage them?

Oded Nir Markusfeld
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Abstract

The term "Production Diseases" referred traditionally to those diseases induced by management practices, metabolic diseases are typical examples. Recently, the term "Production related diseases" has been enhanced to include other traits, such as infertility, and diseases such as mastitis and lameness that might involve infectious agents but exacerbated by nutritional or managemental factors. The presentation deals with Production Diseases in the context of integrated herd health programs, using periparturient diseases and traits as an example. Studies, based on 9377 lactations of cows calving in the period 1995 through 1998 from the author's practice in 7 Israeli Holstein herds, show that most periparturient diseases and traits are followed by increased culling, lower production associated with late peaks and lower persistency, and impaired fertility. The effects are independent of other diseases, and at times are long lasting. Production Diseases are often multifactorial and appear at the same stage of lactation. Independent relationships among them must be established, so that common cause effects, direct and indirect causal associations, and incidental relationships can be differentiated. Control of Production Diseases often involves various disciplines and therefore calls for a "multivariate approach". Such an approach, centered on the herd, has led to the adaptation of integrated programs for herd health. The programs are characterized by the adaptation of multidisciplinary, multifactorial, and a population approach to clinical entities. Preventive measures and routine examinations are the hard core of programs, but deeper involvement in nutrition, production and economics is called for. A routine monitoring and causal analysis of periparturient traits and diseases, production, fertility and abortions are carried out, relevant data are processed, and monitoring reports are issued routinely. Five different linear regression models evaluate factors responsible for losses of a) peak milk yield; b) economy corrected (ECM) peak milk yield; c) extended 305-d milk yield; d) daily 3.5% FCM in the first 90 days in milk; and e) persistencies. Three different logistic and linear regression models evaluate factors that contribute to a) "non pregnancy to first service"; b) unobserved heat; and c) open days. Narrowing down the field of investigation is essential for an intervention to be efficient. Conclusions are drawn from the epidemiological study and the proposed recommendations are weighed with cost/benefit considerations. Possible losses are quantified and used with expected return value in decision analysis. Production Diseases are at times the outcome of managemental mistakes brought about by the drive for higher yields. Integrated herd health programs help to control the negative effects of management by enhancing production under optimal feeding and management regimens. The estimated contribution of improved management to the Israeli national herd phenotypic increase in yield, and the improved fertility that followed the increase in milk yield presented, show that the goal is within reach.

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什么是生产疾病,我们如何管理它们?
"生产疾病"一词传统上是指由管理做法引起的疾病,代谢性疾病就是典型的例子。最近,"与生产有关的疾病"一词已得到加强,包括其他特征,如不孕症,以及乳腺炎和跛行等疾病,这些疾病可能涉及传染因素,但因营养或管理因素而加剧。本报告以围产期疾病和特征为例,在综合畜群健康计划的背景下处理生产疾病。作者在1995年至1998年期间对7个以色列荷斯坦奶牛群的9377头产奶进行了研究,结果表明,大多数围产期疾病和性状之后,会出现淘汰增加、产奶量下降(高峰较晚、持续性较差)和生育力受损。这种影响与其他疾病无关,有时会持续很长时间。生产疾病往往是多因素的,出现在哺乳期的同一阶段。必须建立它们之间的独立关系,以便区分共同的因果效应、直接和间接的因果关联以及偶然的关系。生产病害的防治往往涉及多个学科,因此需要采取“多元方法”。这种以畜群为中心的方法,导致了畜群健康综合方案的适应。该计划的特点是适应多学科,多因素和临床实体的人口方法。预防措施和例行检查是计划的核心,但需要更深入地参与营养、生产和经济方面的工作。对围产期特征和疾病、生产、生育和流产进行常规监测和原因分析,处理相关数据,定期发布监测报告。五种不同的线性回归模型评估了造成峰值产奶量损失的因素;b)经济修正(ECM)峰值产奶量;C)延长305 d产奶量;d)前90天牛奶中每天添加3.5% FCM;e)持久性。三种不同的逻辑和线性回归模型评估导致a)的因素。“非怀孕至首次服务”;B)未观察到的热;c)开放日。缩小调查范围是有效干预的必要条件。从流行病学研究中得出结论,并根据成本/效益考虑对提出的建议进行权衡。在决策分析中,对可能的损失进行量化,并与预期回报值一起使用。生产病害有时是由于追求更高产量而导致的管理失误造成的。综合畜群健康规划通过在最佳饲养和管理方案下提高产量,有助于控制管理的负面影响。改进管理对以色列全国牛群表型产量增加的估计贡献,以及随之而来的产奶量增加的育性提高,表明这一目标是可以实现的。
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