A scoring system for the assessment of the risk of mortality after partial hepatectomy in patients with chronic liver dysfunction.

Ikuo Nagashima, Tadahiro Takada, Kota Okinaga, Hirokazu Nagawa
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引用次数: 28

Abstract

Background/purpose: The aim of this study is to evaluate a new scoring system, called the chronic liver dysfunction (CLD) score, for prediction of the surgical risk of partial hepatectomy in patients with chronic liver damage. Morbidity and mortality rates after gastroenterological surgery are high in patients with hepatic cirrhosis. Accordingly, it is very important to assess the surgical risk in such patients before surgery. Although the Child classification (or Child-Pugh score) has been a standard system, it did not always accurately predict patients at the risk of mortality after gastroenterological surgery, especially partial hepatectomy.

Methods: In 1985, we established a new system called the CLD score, reviewing the patients undergoing gastroenterological operations at one hospital. In the present study, we prospectively used the CLD score in 256 consecutive patients with chronic liver dysfunction who were treated surgically by partial hepatectomy, and investigated the usefulness of the CLD score concerning mortality. The results were compared with those of the Child-Pugh score (C-P score).

Results: After major hepatectomy, all the patients with CLD score exceeding 1.5 died of hepatic failure. After minor hepatectomy, all the patients with CLD score exceeding 2.5 died of hepatic failure. On the other hand, C-P score did not predict the outcome in these patients.

Conclusions: Compared with the C-P score, which was considered the gold standard scoring system for assessing surgical risk for patients with chronic liver dysfunction, our CLD score provides a more reliable assessment of the risk of partial hepatectomy.

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慢性肝功能不全患者部分肝切除术后死亡风险评估的评分系统。
背景/目的:本研究的目的是评估一种新的评分系统,称为慢性肝功能障碍(CLD)评分,用于预测慢性肝损害患者部分肝切除术的手术风险。肝硬化患者在胃肠外科手术后的发病率和死亡率都很高。因此,术前评估此类患者的手术风险是非常重要的。虽然Child分类(或Child- pugh评分)已经成为一个标准系统,但它并不总是准确地预测患者在胃肠外科手术后的死亡风险,特别是部分肝切除术。方法:1985年,我们建立了一种新的CLD评分系统,对一家医院接受胃肠外科手术的患者进行评分。在本研究中,我们前瞻性地对256例经部分肝切除术治疗的连续慢性肝功能障碍患者使用CLD评分,并研究CLD评分与死亡率的相关性。将结果与Child-Pugh评分(C-P评分)进行比较。结果:大肝切除术后,CLD评分超过1.5分的患者均死于肝功能衰竭。小肝切除术后,CLD评分超过2.5的患者均死于肝功能衰竭。另一方面,C-P评分并不能预测这些患者的预后。结论:与被认为是评估慢性肝功能障碍患者手术风险的金标准评分系统C-P评分相比,我们的CLD评分对肝部分切除术的风险提供了更可靠的评估。
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