Does intermittent hypoxia increase erythropoiesis in professional cyclists during a 3-week race?

José G Villa, Alejandro Lucía, José A Marroyo, Concepción Avila, Fernando Jiménez, Juan Garcia-López, Conrad P Earnest, Alfredo Córdova
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引用次数: 16

Abstract

In this study we examined the effects of intermittent hypoxia exposure (IHE) in a group of professional cyclists (n = 6; age 26 +/- 1 yr) competing in the 2001 Vuelta a España. After each daily stage, treated subjects received four 5-min bouts of normobaric IHE (mean O2 concentration of 12.6%, simulating a mean altitude of 4,000 m) interspersed with 5-min bouts of breathing hotel room air (normoxia) until completing a total IHE of 20-min duration. The primary outcome, compared to a control group of similar characteristics not receiving IHE (n = 5; age 25 +/- 1 yr), was the % increase in erythropoietin (Epo) from the beginning to the end of the Vuelta. Statistical analysis showed that Epo increase tended to be higher (p = 0.052) in the IHE group than in controls (37.4 +/- 5.8% vs. -4.4 +/- 19.5%, respectively). However IHE had no effect on reticulocytes or erythrocyte count (p > 0.05).

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间歇缺氧会增加职业自行车运动员在3周比赛中的红细胞生成吗?
在这项研究中,我们检查了间歇性缺氧暴露(IHE)对一组职业自行车运动员的影响(n = 6;年龄26岁(±1岁)参加2001年环法自行车赛España。在每个每日阶段结束后,治疗对象接受4次5分钟的常压IHE(平均O2浓度为12.6%,模拟平均海拔4000米),穿插5分钟的酒店房间空气呼吸(常氧),直到完成总持续时间20分钟的IHE。与未接受IHE治疗的具有相似特征的对照组(n = 5;年龄25 +/- 1岁),从环法开始到结束红细胞生成素(Epo)的百分比增加。统计学分析显示,IHE组Epo升高趋势高于对照组(分别为37.4 +/- 5.8%和-4.4 +/- 19.5%)(p = 0.052)。而IHE对网织红细胞和红细胞计数无影响(p > 0.05)。
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