Increasing hepatitis B vaccine coverage in prisons in England and Wales.

R L Gilbert, A Costella, M Piper, O N Gill
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Abstract

The most frequently reported risk factor for hepatitis B infection in England and Wales is injecting drug use (38%). Since approximately 61% of injecting drug users (IDUs) had been imprisoned and less than 40% had received hepatitis B vaccine, a prison based hepatitis B vaccination programme was set up in 2001. At the 42 establishments participating in this study, all prisoners were offered vaccine at reception. Prisoners over 18 years were vaccinated using the 0, 7 and 21 days schedule and those under 18 years, using the 0, 1 and 2 months schedule. As far as possible a fourth dose was given to all after 12 months. In 2003, 14,163 prisoners received at least one dose of vaccine and altogether 26,265 doses were administered. A further 1111 prisoners reported they had already been vaccinated against hepatitis B. The median vaccine coverage rate was 17% (range 0-94%). Despite low coverage levels, the vaccination programme in prisons can be said to have vaccinated a sizable number of young, male prisoners, a group that have previously been shown to be at high risk of infection. The prisons which achieved vaccine coverage levels over 50% had designated nursing staff who ran the vaccination clinics.

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增加英格兰和威尔士监狱的乙肝疫苗覆盖率。
在英格兰和威尔士,最常见的乙型肝炎感染危险因素是注射吸毒(38%)。由于大约61%的注射吸毒者被监禁,不到40%的人接种了乙肝疫苗,2001年设立了一个以监狱为基础的乙肝疫苗接种方案。在参与这项研究的42个机构中,所有囚犯在接待时都获得了疫苗。18岁以上的囚犯按0、7和21天接种疫苗,18岁以下的囚犯按0、1和2个月接种疫苗。12个月后尽可能给所有人注射第四剂。2003年,14 163名囚犯至少接种了一剂疫苗,总共接种了26 265剂疫苗。另有1111名囚犯报告说,他们已经接种了乙型肝炎疫苗,疫苗覆盖率中位数为17%(范围0-94%)。尽管覆盖率很低,但可以说,监狱中的疫苗接种方案为相当数量的年轻男性囚犯接种了疫苗,这一群体以前已被证明具有很高的感染风险。疫苗接种率达到50%以上的监狱有指定的护理人员管理疫苗接种诊所。
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