{"title":"N-Terminal-proBNP (NT-proBNP) as an indicator of cardiac dysfunction. A study in patients presenting with suspected cardiac disorders.","authors":"G Hess, J Moecks, D Zdunek","doi":"10.1007/s00392-005-0205-6","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Natriuretic peptides represent a novel diagnostic tool in the assessment of cardiac dysfunction.</p><p><strong>Methods: </strong>A total of 473 consecutive referred patients presenting to 18 cardiologists for the assessment of their cardiac state were recruited for the study. Patients received a medical history, a physical examination an electrocardiogram and an echocardiogram where left ventricular ejection fraction was recorded.</p><p><strong>Results: </strong>NT-proBNP was found to correlate with left ventricular ejection fraction (LVEF), level of symptoms (NYHA classification), history of angina pectoris (AP) and myocardial infarction (AMI). Atrial fibrillation (AF) and thyroid dysfunction as well as renal impairment were shown to influence NT-proBNP levels.</p><p><strong>Conclusion: </strong>The study supports the hypothesis that NT-proBNP determination contributes to the assessment of patients presenting to cardiologists.</p>","PeriodicalId":23757,"journal":{"name":"Zeitschrift fur Kardiologie","volume":"94 4","pages":"247-54"},"PeriodicalIF":0.0000,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00392-005-0205-6","citationCount":"18","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur Kardiologie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s00392-005-0205-6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 18
Abstract
Background: Natriuretic peptides represent a novel diagnostic tool in the assessment of cardiac dysfunction.
Methods: A total of 473 consecutive referred patients presenting to 18 cardiologists for the assessment of their cardiac state were recruited for the study. Patients received a medical history, a physical examination an electrocardiogram and an echocardiogram where left ventricular ejection fraction was recorded.
Results: NT-proBNP was found to correlate with left ventricular ejection fraction (LVEF), level of symptoms (NYHA classification), history of angina pectoris (AP) and myocardial infarction (AMI). Atrial fibrillation (AF) and thyroid dysfunction as well as renal impairment were shown to influence NT-proBNP levels.
Conclusion: The study supports the hypothesis that NT-proBNP determination contributes to the assessment of patients presenting to cardiologists.
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