Direct percutaneous ethanol instillation for treatment of venous malformation in the face and neck

Chih-Hsien Lee, Shyi-Gen Chen
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引用次数: 82

Abstract

Venous malformations of the face and neck involve multiple anatomical spaces and encase critical neuromuscular structures, making surgical treatment difficult; high recurrence rates and high morbidity are well documented. Various methods of treatment of uncertain value and risk of complications have been advocated. We present our experience in treating five patients with venous malformation in the face and neck by using direct percutaneous ethanol sclerotherapy. Four patients had large lesions (≥3 cm; one patient had two large lesions in the low eyelid), and the other had a mid-sized lesion (1.5–3 cm). Under general or local anaesthesia, one-third to one-quarter cavity volume of ethanol was injected percutaneously, directly into the malformation with under fluoroscopy [de Lorimier AA. Sclerotherapy for venous malformations. J Pediatr Surg 1995;30:188–93; Johnson PL, Eckard DA, Brecheisen MA, Girod DA, Tsue TT. Percutaneous ethanol sclerotherapy of venous malformations of the tongue. Am J Neuroradiol 2002;23:779–82; Pappas DC Jr, Persky MS, Berenstein A. Evaluation and treatment of head and neck venous vascular malformations. Ear Nose Throat J 1998;77:914–22; Lee CH, Chen SG. Direct percutaneous ethanol sclerotherapy for treatment of a recurrent venous malformation in the periorbital region. ANZ J Surg. 2004;74(12):1126–7. 1, 2, 3, 4]. Four patients required two injections. All patients had remission and alleviation of their symptoms, with no major complications. Direct percutaneous injection of absolute ethanol provides a simple and reliable alternative treatment for venous malformation in the face and neck.

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直接经皮滴注乙醇治疗面部及颈部静脉畸形
面部和颈部静脉畸形涉及多个解剖空间,并包围关键的神经肌肉结构,使手术治疗困难;高复发率和高发病率是有据可查的。各种治疗方法的价值不确定和并发症的风险被提倡。我们报告用直接经皮乙醇硬化疗法治疗5例面部及颈部静脉畸形的经验。4例患者病变较大(≥3cm;一名患者下眼睑有两个较大的病变,另一名患者有一个中等大小的病变(1.5-3厘米)。在全身或局部麻醉下,在透视下经皮将三分之一至四分之一腔容量的乙醇直接注入畸形处[de Lorimier AA]。静脉畸形的硬化治疗。中华儿科杂志(英文版);1993;Johnson PL, Eckard DA, Brecheisen MA, Girod DA, Tsue TT。经皮乙醇硬化治疗舌静脉畸形。[J]中华神经科杂志2002;23:779-82;杨建军,杨建军,李建军,等。头颈部静脉血管畸形的诊断与治疗。耳鼻咽喉[J]; 1998; 77:914-22;李超,陈绍光。直接经皮乙醇硬化疗法治疗眼眶周围静脉畸形复发。中华外科杂志。2004;21(1):1 - 7。1,2,3,4]。4名患者需要两次注射。所有患者的症状均得到缓解和缓解,无重大并发症。直接经皮注射无水乙醇为面部和颈部静脉畸形提供了一种简单可靠的替代治疗方法。
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