A histological study of the effects of enzootic abortion of ewes virus in the lactating bovine mammary gland.

A H Corner, G L Bannister, D P Hill
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Abstract

Inoculation of the udders of cows with the virus of enzootic abortion of ewes resulted in a severe acute mastitis. The mastitis was characterized clinically by pyrexia, anorexia, decreased milk production, swelling and marked alteration in the physical quality of the milk. The basic lesion was necrosis of alveolar and duct epithelial cells. Virus particles were demonstrated in all levels of the mammary gland three days after inoculation illustrating the rapid spread of the agent. Cells resembling Reed-Sternberg cells and similar to those seen in experimental mastitis produced by the virus of infectious bovine rhinotracheitis were seen in tissues collected six and nine days after inoculation.

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母羊病毒在哺乳期牛乳腺内地方性流产影响的组织学研究。
用母羊地方性流产病毒接种奶牛乳房,可引起严重的急性乳腺炎。乳腺炎临床表现为发热、厌食、产奶量减少、肿胀、乳质明显改变。基本病变为肺泡和导管上皮细胞坏死。接种三天后,在乳腺的各个层次上都发现了病毒颗粒,说明了该剂的迅速传播。在接种后6天和9天收集的组织中,可以看到类似里德-斯滕伯格细胞的细胞和类似于传染性牛鼻气管炎病毒产生的实验性乳腺炎中的细胞。
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