The impact of menstrual side effects on contraceptive discontinuation: findings from a longitudinal study in Cairo, Egypt.

Elizabeth Tolley, Sarah Loza, Laila Kafafi, Stirling Cummings
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引用次数: 105

Abstract

Context: Although many research studies have documented the relationship between menstrual side effects of contraceptives and discontinuation of use, few have sought to identify factors that predispose women to discontinue because of changes in bleeding patterns. Such information is important to enable family planning providers to better help women and couples choose appropriate methods and use them successfully.

Methods: Forty-eight women participating in six focus group discussions described their experiences using the IUD, the hormonal implant or the three-month injectable. Subsequently, 259 women using one of these methods for the first time were followed for up to 18 months to determine patterns of menstrual bleeding and perceptions of menstrual cycle change over time. Multivariable analytical methods were used to examine the associations between selected measures and method discontinuation.

Results: Contraceptive discontinuation differed by method: Nearly 70% of injectable users had stopped using their chosen method after one year, compared with 34% of IUD users and 10% of implant users. Before initiating a method, women reported an average of five bleeding days per cycle. During the first six months of use, IUD users reported an average of six days of bleeding per cycle; injectable and implant users reported 11-12. In multivariable models, each additional day of bleeding was significantly associated with a 2-4% increase in discontinuation, depending on method type. Among IUD users, women whose husbands knew that they had visited a clinic to initiate a method were less likely than others to discontinue method use (hazard ratio, -1.9). Age was significantly associated with decreased discontinuation among implant users.

Conclusion: Counseling about bleeding and other side effects should be tailored to women's personal contexts and contraceptive experiences.

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经期副作用对停止避孕的影响:来自埃及开罗纵向研究的结果。
背景:尽管许多研究已经证明了避孕药的月经副作用和停止使用之间的关系,但很少有研究试图确定因出血模式改变而使妇女易停止使用避孕药的因素。这些信息对于计划生育提供者能够更好地帮助妇女和夫妇选择适当的方法并成功地使用这些方法非常重要。方法:48名妇女参加了6次焦点小组讨论,描述了她们使用宫内节育器、激素植入或三个月注射的经历。随后,259名首次使用其中一种方法的妇女进行了长达18个月的随访,以确定月经出血的模式和月经周期随时间的变化。使用多变量分析方法来检查所选措施与方法中断之间的关联。结果:不同的避孕方法有不同:近70%的注射使用者在一年后停止使用他们选择的方法,相比之下,34%的宫内节育器使用者和10%的植入使用者停止使用他们选择的方法。在开始使用这种方法之前,女性报告平均每个月经周期出血五天。在使用前6个月,宫内节育器使用者报告平均每个周期出血6天;注射和植入使用者报告11-12。在多变量模型中,根据方法类型,每增加一天出血与停药率增加2-4%显著相关。在宫内节育器使用者中,丈夫知道她们曾到诊所开始使用避孕方法的妇女比其他人更不可能停止使用避孕方法(风险比为-1.9)。年龄与种植体使用者中停止使用的减少显著相关。结论:关于出血和其他副作用的咨询应根据妇女的个人情况和避孕经历进行调整。
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