Utilization of follow-up specimens from viremic blood donors to assess the value of west nile virus immunoglobulin G avidity as an indicator of recent infection.

Harry E Prince, Mary Lapé-Nixon, Michael P Busch, Leslie H Tobler, Gregory A Foster, Susan L Stramer
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引用次数: 9

Abstract

The value of West Nile virus immunoglobulin G avidity for distinguishing recent from past infection was investigated using 348 follow-up specimens from 170 viremic blood donors. Low avidity accurately indicated infection within the previous 4 months. However, due to rapid avidity maturation in some individuals, high avidity did not accurately indicate past infection.

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利用病毒血症献血者的随访标本,评估西尼罗病毒免疫球蛋白G含量作为近期感染指标的价值。
利用来自170名病毒血症献血者的348份随访标本,研究了西尼罗病毒免疫球蛋白G对区分最近和过去感染的价值。低贪婪度准确指示感染前4个月内。然而,由于某些个体的贪婪度成熟迅速,高贪婪度并不能准确地指示过去的感染。
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