Clinical Characteristics of Mother-Infant Dyad and Placental Pathology in COVID-19 Cases in Predominantly African American Population.

IF 0.8 Q4 PEDIATRICS AJP Reports Pub Date : 2021-01-01 Epub Date: 2021-02-01 DOI:10.1055/s-0040-1721673
Sanket Jani, Suzanne M Jacques, Faisal Qureshi, Girija Natarajan, Sujit Bajaj, Pradeep Velumula, Cindy Agu, Monika Bajaj
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引用次数: 13

Abstract

Objective  In this currently evolving coronavirus disease 2019 (COVID-19) pandemic, the evidence is scarce about the impact of COVID-19 infection on women in labor and neonates in an inner city African-Americans (AA) population. The objective of this study was to evaluate the clinical outcomes and placental pathology in mother-infant dyads in COVID-19 cases. Study Design  Retrospective chart review was conducted on 34 COVID-19 positive mother-infant dyads to study their baseline characteristics and outcomes. Placental pathology was reviewed by two perinatal pathologists. Results  COVID-19 was noted in 3% of pregnant women who delivered in our institution. The majority (82%) of them were asymptomatic. Out of the four mothers who were symptomatic, only three (9%) required supplemental oxygen. None of them required invasive ventilation. All the neonates tested negative for COVID-19 at 24 hours of age. There were no gross or microscopic pathological abnormalities detected that could be definitely associated with any COVID-19 related complications during pregnancy in any of the 34 placentas. Conclusion  COVID-19 does not appear to increase morbidity and mortality among pregnant women and their neonates in a predominantly AA population. Our study did not find any evidence of vertical transmission of COVID-19 infection nor any specific findings on placental pathology. Key Points Majority of women infected by coronavirus disease 2019 (COVID-19) during labor were asymptomatic.None of the newborns tested positive for COVID-19 at 24 hours of age.Placental pathology findings were nonspecific in COVID-19 mothers.

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以非洲裔美国人为主的COVID-19病例母婴双体和胎盘病理的临床特征
在当前不断演变的2019冠状病毒病(COVID-19)大流行中,关于COVID-19感染对内城非洲裔美国人(AA)人群中分娩妇女和新生儿的影响的证据很少。本研究的目的是评估COVID-19病例母婴双体的临床结局和胎盘病理。研究设计对34例COVID-19阳性母婴进行回顾性图表复习,研究其基线特征和结局。两位围产期病理学家回顾了胎盘病理学。结果在我院分娩的孕妇中,新冠肺炎检出率为3%。大多数(82%)患者无症状。在有症状的四位母亲中,只有三位(9%)需要补充氧气。他们都不需要有创通气。所有新生儿在24小时时COVID-19检测均为阴性。在34个胎盘中,没有发现任何明显与妊娠期间任何COVID-19相关并发症相关的肉眼或显微镜病理异常。结论在以AA为主的人群中,COVID-19并未增加孕妇及其新生儿的发病率和死亡率。我们的研究未发现COVID-19感染垂直传播的任何证据,也未发现胎盘病理学的任何具体发现。新型冠状病毒病(COVID-19)感染妇女产程中多数无症状。这些新生儿在24小时内都没有COVID-19检测呈阳性。COVID-19母亲的胎盘病理结果无特异性。
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来源期刊
AJP Reports
AJP Reports PEDIATRICS-
CiteScore
2.20
自引率
0.00%
发文量
30
审稿时长
12 weeks
期刊最新文献
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