{"title":"Medical abortion at 13 or more weeks gestation provided through telemedicine: A retrospective review of services","authors":"Nathalie Kapp , Kathryn Andersen , Risa Griffin , Amalia Puri Handayani , Marlies Schellekens , Rebecca Gomperts","doi":"10.1016/j.conx.2021.100057","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><p>To evaluate medical abortion effectiveness and safety in women at 13 or more weeks gestation provided care through Women on Web's telemedicine service.</p></div><div><h3>Study Design</h3><p>We conducted a retrospective case study of abortions at 13 or more weeks gestation provided by Women on Web between 2016 and 2019. Women received mifepristone and misoprostol or misoprostol alone for abortion. We extracted demographic characteristics and outcome data for cases with pregnancy continuation outcomes.</p></div><div><h3>Results</h3><p>We identified 144 women who used medical abortion at 13 or more weeks; 131 (91%) provided abortion outcome data. Almost all, 118 (90%) received mifepristone and misoprostol. The population had an average age of 26 ± 5.8 years, 102 (78%) reported a gestational age of 13 to 15 weeks, 114 (87%) had experienced prior pregnancy, and represented all world regions. Overall, 13 (10%) women reported a continuing pregnancy, with 5 (5%) among women 13 to 15 weeks and 8 (28%) among those ≥16 weeks (<em>p</em> = 0.001); 38 (29%) reported adverse events (heavy bleeding, fever), 53 (43%) sought additional care from a health provider, and 18% of all cases received treatment with D&C/aspiration.</p></div><div><h3>Conclusions</h3><p>Efficacy of self-administered medical abortion decreases as gestational age increases, risking continuation of pregnancy. Provision through telemedicine at 13 to 15 weeks appears safe and effective.</p></div><div><h3>Implications</h3><p>Limited data suggest that medical abortion through telemedicine services may be a safe option through 15 weeks gestation in settings where there is ready access to the formal health system. More research with adequate sample sizes and high rates of follow-up is needed to inform on the safety of telemedicine for pregnancies 13 weeks and greater.</p></div>","PeriodicalId":10655,"journal":{"name":"Contraception: X","volume":"3 ","pages":"Article 100057"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.conx.2021.100057","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Contraception: X","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2590151621000046","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 7
Abstract
Objectives
To evaluate medical abortion effectiveness and safety in women at 13 or more weeks gestation provided care through Women on Web's telemedicine service.
Study Design
We conducted a retrospective case study of abortions at 13 or more weeks gestation provided by Women on Web between 2016 and 2019. Women received mifepristone and misoprostol or misoprostol alone for abortion. We extracted demographic characteristics and outcome data for cases with pregnancy continuation outcomes.
Results
We identified 144 women who used medical abortion at 13 or more weeks; 131 (91%) provided abortion outcome data. Almost all, 118 (90%) received mifepristone and misoprostol. The population had an average age of 26 ± 5.8 years, 102 (78%) reported a gestational age of 13 to 15 weeks, 114 (87%) had experienced prior pregnancy, and represented all world regions. Overall, 13 (10%) women reported a continuing pregnancy, with 5 (5%) among women 13 to 15 weeks and 8 (28%) among those ≥16 weeks (p = 0.001); 38 (29%) reported adverse events (heavy bleeding, fever), 53 (43%) sought additional care from a health provider, and 18% of all cases received treatment with D&C/aspiration.
Conclusions
Efficacy of self-administered medical abortion decreases as gestational age increases, risking continuation of pregnancy. Provision through telemedicine at 13 to 15 weeks appears safe and effective.
Implications
Limited data suggest that medical abortion through telemedicine services may be a safe option through 15 weeks gestation in settings where there is ready access to the formal health system. More research with adequate sample sizes and high rates of follow-up is needed to inform on the safety of telemedicine for pregnancies 13 weeks and greater.
目的评价妇女网上远程医疗服务对妊娠13周及以上妇女进行药物流产的有效性和安全性。研究设计我们对2016年至2019年期间由Women on Web提供的妊娠13周及以上流产病例进行了回顾性研究。妇女在流产时使用米非司酮和米索前列醇或单独使用米索前列醇。我们提取了有妊娠结局的病例的人口学特征和结局数据。结果144例妊娠13周及以上采用药物流产的孕妇;131例(91%)提供流产结局数据。几乎所有118例(90%)接受了米非司酮和米索前列醇治疗。人口平均年龄为26±5.8岁,102人(78%)报告胎龄为13至15周,114人(87%)有过妊娠史,代表了世界所有地区。总体而言,13名(10%)妇女报告继续妊娠,13至15周妇女中有5名(5%),≥16周妇女中有8名(28%)(p = 0.001);38例(29%)报告了不良事件(大出血、发烧),53例(43%)向卫生服务提供者寻求额外护理,18%的病例接受了D&C/抽吸治疗。结论自行药物流产的有效性随胎龄的增加而降低,存在继续妊娠的风险。13至15周通过远程医疗提供似乎是安全有效的。影响有限的数据表明,在可以随时进入正规卫生系统的环境中,通过远程医疗服务在妊娠15周内进行药物流产可能是一种安全的选择。需要进行更多具有足够样本量和高随访率的研究,以了解远程医疗对怀孕13周及以上孕妇的安全性。