Use of biologics in food allergy management.

Allergologie Select Pub Date : 2021-02-19 eCollection Date: 2021-01-01 DOI:10.5414/ALX02141E
Margitta Worm, Wojciech Francuzik, Sabine Dölle-Bierke, Aikaterina Alexiou
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引用次数: 3

Abstract

Food allergies are a common medical problem, with children being the most affected patient group. The standard of care of food allergy consists of the acute treatment in case of a reaction and food avoidance in the long term, which influences the quality of life of patients. In this article, current developments for the causal treatment of food allergy including specific immunotherapy and biologics will be discussed. Epicutaneous and oral immunotherapy are currently in clinical development for the treatment of food allergy, and the results demonstrate good tolerability and efficacy with an increase in the oral threshold level. Biologics and, in particular, anti-IgE are currently investigated for their therapeutic use in food allergies. The results are promising, suggesting efficacy and tolerability.

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生物制剂在食物过敏管理中的应用。
食物过敏是一种常见的医学问题,儿童是受影响最大的患者群体。食物过敏的护理标准包括发生反应时的急性治疗和长期的食物避免,这影响了患者的生活质量。本文将对食物过敏病因治疗的最新进展,包括特异性免疫治疗和生物制剂进行讨论。表皮免疫疗法和口服免疫疗法目前正处于治疗食物过敏的临床开发阶段,结果显示出良好的耐受性和有效性,并且口服阈值水平有所提高。生物制剂,特别是抗ige,目前正在研究它们在食物过敏中的治疗用途。结果是有希望的,表明疗效和耐受性。
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Vegan diets from an allergy point of view - Position paper of the DGAKI working group on food allergy. Clinical endpoints in allergen immunotherapy: State of the art 2022. Allergic asthma: An indication for allergen immunotherapy. Allergen challenge tests in allergen immunotherapy: State of the art. Real-life evidence in allergen immunotherapy: Moving forward with mHealth apps.
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