A case report of greater saphenous vein thrombosis in a patient with coronavirus (COVID-19) infection.

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2021-03-03 DOI:10.1186/s40794-021-00131-9

Negin Hesam-Shariati, Poya Fatehi, Fardin Fathi, Morteza Abouzaripour, Mohammad Bakhtiar Hesam Shariati

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Abstract

In December 2019, the World Health Organization (WHO) announced a series of pneumonia cases caused by an unknown origin, discovered in Wuhan, China. A dangerous virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a disease named acute respiratory syndrome, which was later popularly called coronavirus infection (COVID-19). Patients with acute COVID-19 are at high risk of thrombosis in various blood vessels due to hypercoagulability, blood stasis, and endothelial damage. In this study, we present a case report of a patient with COVID-19, who was hospitalized in one of the hospitals in Sanandaj, Iran. There were symptoms of fever, chills, muscle aches, cough, and tachycardia. Laboratory tests showed high levels of CRP, ESR, Ferritin CLIA, LDH and D-Dimer in this patient. Doppler ultrasound of the patient also revealed an abnormal finding, thrombosis in the right greater saphenous vein. This suggests that COVID-19 may lead to other negative effects through damage to blood vessels.

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冠状病毒（COVID-19）感染患者大隐静脉血栓形成病例报告。

2019 年 12 月，世界卫生组织（WHO）公布了在中国武汉发现的一系列不明原因肺炎病例。一种名为严重急性呼吸系统综合征冠状病毒2（SARS-CoV-2）的危险病毒引发了一种名为急性呼吸系统综合征的疾病，后来被人们称为冠状病毒感染（COVID-19）。急性 COVID-19 患者由于高凝状态、血液淤滞和内皮损伤，极易在各种血管中形成血栓。在本研究中，我们报告了一例在伊朗萨南达季一家医院住院治疗的 COVID-19 患者。患者出现发热、寒战、肌肉疼痛、咳嗽和心动过速等症状。实验室检查显示该患者的 CRP、ESR、Ferritin CLIA、LDH 和 D-Dimer 水平较高。对患者进行的多普勒超声检查也发现了异常，即右大隐静脉血栓形成。这表明 COVID-19 可能会通过损伤血管导致其他负面影响。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464

期刊介绍： ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.