Lindsay Somerville, Amber Cardani, Thomas J Braciale
{"title":"Alveolar Macrophages in Influenza A Infection Guarding the Castle with Sleeping Dragons.","authors":"Lindsay Somerville, Amber Cardani, Thomas J Braciale","doi":"10.31038/idt.2020114","DOIUrl":null,"url":null,"abstract":"Despite major advances in influenza vaccination and flu-prevention community awareness campaigns, Influenza A virus (IAV) remains a worldwide and recurring threat [1, 2]. Seasonal influenza causes 3-5 million cases of severe respiratory and systemic illness and upwards of 650,000 deaths annually, particularly among the elderly, very young, and chronically ill [3]. Countless hours of missed school and work have significant economic consequences [4, 5]. In pandemic years, morbidity and mortality soars, especially among the young [6, 7].","PeriodicalId":87272,"journal":{"name":"Infectious diseases and therapeutics","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935064/pdf/nihms-1662418.pdf","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infectious diseases and therapeutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31038/idt.2020114","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/5/15 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
Abstract
Despite major advances in influenza vaccination and flu-prevention community awareness campaigns, Influenza A virus (IAV) remains a worldwide and recurring threat [1, 2]. Seasonal influenza causes 3-5 million cases of severe respiratory and systemic illness and upwards of 650,000 deaths annually, particularly among the elderly, very young, and chronically ill [3]. Countless hours of missed school and work have significant economic consequences [4, 5]. In pandemic years, morbidity and mortality soars, especially among the young [6, 7].