riboCIRC: a comprehensive database of translatable circRNAs.

IF 12.3 1区 生物学 Q1 Agricultural and Biological Sciences Genome Biology Pub Date : 2021-03-08 DOI:10.1186/s13059-021-02300-7
Huihui Li, Mingzhe Xie, Yan Wang, Ludong Yang, Zhi Xie, Hongwei Wang
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Abstract

riboCIRC is a translatome data-oriented circRNA database specifically designed for hosting, exploring, analyzing, and visualizing translatable circRNAs from multi-species. The database provides a comprehensive repository of computationally predicted ribosome-associated circRNAs; a manually curated collection of experimentally verified translated circRNAs; an evaluation of cross-species conservation of translatable circRNAs; a systematic de novo annotation of putative circRNA-encoded peptides, including sequence, structure, and function; and a genome browser to visualize the context-specific occupant footprints of circRNAs. It represents a valuable resource for the circRNA research community and is publicly available at http://www.ribocirc.com .

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riboCIRC:可翻译 circRNAs 的综合数据库。
riboCIRC 是一个以翻译组数据为导向的 circRNA 数据库,专门用于托管、探索、分析和可视化来自多物种的可翻译 circRNA。该数据库提供了一个计算预测的核糖体相关 circRNAs 的综合资料库;一个人工编辑的经实验验证的翻译 circRNAs 库;对可翻译 circRNAs 的跨物种保护进行评估;对推测的 circRNA 编码肽进行系统的从头注释,包括序列、结构和功能;以及一个基因组浏览器,用于可视化 circRNAs 在特定环境中的占位足迹。它是 circRNA 研究界的宝贵资源,可通过 http://www.ribocirc.com 公开获取。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Genome Biology
Genome Biology BIOTECHNOLOGY & APPLIED MICROBIOLOGY-GENETICS & HEREDITY
CiteScore
25.50
自引率
3.30%
发文量
0
审稿时长
14 weeks
期刊介绍: Genome Biology is a leading research journal that focuses on the study of biology and biomedicine from a genomic and post-genomic standpoint. The journal consistently publishes outstanding research across various areas within these fields. With an impressive impact factor of 12.3 (2022), Genome Biology has earned its place as the 3rd highest-ranked research journal in the Genetics and Heredity category, according to Thomson Reuters. Additionally, it is ranked 2nd among research journals in the Biotechnology and Applied Microbiology category. It is important to note that Genome Biology is the top-ranking open access journal in this category. In summary, Genome Biology sets a high standard for scientific publications in the field, showcasing cutting-edge research and earning recognition among its peers.
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