Red Blood Cell Distribution Width Trajectory During a Multicomponent Exercise in Hospitalized Older Adults: A Secondary Analysis of a Randomized Clinical Trial.
Nicolás Martínez-Velilla, Robinson Ramírez-Vélez, Mikel L Sáez de Asteasu, Fabricio Zambom-Ferraresi, Antonio García-Hermoso, Itxaso Marín-Epelde, Mikel Izquierdo
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引用次数: 3
Abstract
There is emerging evidence that emphasizes RDW as an optimal prognostic biomarker for cardiovascular diseases (Rejuvenation Research: https://pubmed.ncbi.nlm.nih.gov/30572793/ https://pubmed.ncbi.nlm.nih.gov/30132390/). However, there is hardly any evidence of interventions that are capable of modifying RDW. Our aim was to investigate the association of RDW levels and the response to an individualized exercise program in hospitalized older adults. To our knowledge, this is the first study that specifically looks at the impact of an intervention in this parameter among very old hospitalized patients. We have failed to show any change, but we consider that this result is also important in order to continue with the research of the strong correlation of RDW and different biological pathways.
期刊介绍：
Rejuvenation Research publishes cutting-edge, peer-reviewed research on rejuvenation therapies in the laboratory and the clinic. The Journal focuses on key explorations and advances that may ultimately contribute to slowing or reversing the aging process, and covers topics such as cardiovascular aging, DNA damage and repair, cloning, and cell immortalization and senescence.
Rejuvenation Research coverage includes:
Cell immortalization and senescence
Pluripotent stem cells
DNA damage/repair
Gene targeting, gene therapy, and genomics
Growth factors and nutrient supply/sensing
Immunosenescence
Comparative biology of aging
Tissue engineering
Late-life pathologies (cardiovascular, neurodegenerative and others)
Public policy and social context.
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