Arthrocentesis of the Temporomandibular Joint: Systematic Review and Clinical Implications of Research Findings.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2021-12-01 DOI:10.11607/ofph.2606
Luca Guarda-Nardini, Andrè Mariz De Almeida, Daniele Manfredini
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引用次数: 19

Abstract

Aims: To review randomized clinical trials on arthrocentesis for managing temporomandibular disorders (TMD) and to discuss the clinical implications.

Methods: On March 10, 2019, a systematic search of relevant articles published over the last 20 years was performed in PubMed, as well as in Scopus, the authors' personal libraries, and the reference lists of included articles. The focus question was: In patients with TMD (P), does TMJ arthrocentesis (I), compared to any control treatment (C), provide positive outcomes (O)?

Results/conclusion: Thirty papers were included comparing TMJ arthrocentesis to other treatment protocols in patients with disc displacement without reduction and/or closed lock (n = 11), TMJ arthralgia and/or unspecific internal derangements (n = 8), or TMJ osteoarthritis (n = 11). In general, the consistency of the findings was poor because of the heterogenous study designs, and so caution is required when interpreting the meta-analyses. In summary, it can be suggested that TMJ arthrocentesis improves jaw function and reduces pain levels, and the execution of multiple sessions (three to five) is superior to a single session (effect size = 1.82). Comparison studies offer inconsistent findings, with the possible exception of the finding that splints are superior in managing TMJ pain (effect size = 1.36) compared to arthrocentesis, although this conclusion is drawn from very heterogenous studies (I2 = 94%). The additional use of cortisone is not effective for improving outcomes, while hyaluronic acid or platelet-rich plasma positioning may have additional value according to some studies. The type of intervention, the baseline presence of MRI effusion, and the specific Axis I diagnosis do not seem to be important predictors of effectiveness, suggesting that, as in many pain medicine fields, efforts to identify predictors of treatment outcome should focus more on the patient (eg, age, psychosocial impairment) than the disease.

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颞下颌关节穿刺:系统回顾和研究结果的临床意义。
目的:回顾关节穿刺治疗颞下颌紊乱(TMD)的随机临床试验,并讨论其临床意义。方法:于2019年3月10日,系统检索PubMed、Scopus、作者个人图书馆以及收录文章的参考文献列表中近20年来发表的相关文章。焦点问题是:在TMD (P)患者中,与任何对照治疗(C)相比,TMJ关节穿刺(I)是否提供积极的结果(O)?结果/结论:纳入了30篇论文,比较了TMJ关节穿刺与其他治疗方案在未复位和/或闭锁椎间盘移位(n = 11)、TMJ关节痛和/或非特异性内部紊乱(n = 8)或TMJ骨关节炎(n = 11)患者中的应用。总的来说,由于研究设计的异质性,研究结果的一致性较差,因此在解释meta分析时需要谨慎。综上所述,可以认为TMJ关节穿刺改善了下颌功能并减少了疼痛水平,并且多次(3 - 5次)的执行优于单次(效应值= 1.82)。比较研究提供了不一致的结果,可能有一个例外,即夹板在治疗TMJ疼痛方面优于关节穿刺(效应值= 1.36),尽管这一结论来自非常不同的研究(I2 = 94%)。根据一些研究,额外使用可的松对改善预后没有效果,而透明质酸或富血小板血浆定位可能有额外的价值。干预类型、MRI渗出的基线存在和特定的轴I诊断似乎不是有效性的重要预测因素,这表明,正如在许多疼痛医学领域一样,确定治疗结果预测因素的努力应更多地关注患者(例如,年龄、社会心理障碍)而不是疾病。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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