[The effects of normal tissue objective parameters on lung stereotactic body radiotherapy dose distributions].

Q4 Medicine Magyar onkologia Pub Date : 2021-03-17 Epub Date: 2020-03-17
Mercédesz Gerdán, Tamás Pócza, Csaba Polgár, Tibor Major
{"title":"[The effects of normal tissue objective parameters on lung stereotactic body radiotherapy dose distributions].","authors":"Mercédesz Gerdán,&nbsp;Tamás Pócza,&nbsp;Csaba Polgár,&nbsp;Tibor Major","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>In treatment planning of small-sized lung tumors treated with stereotactic body radiotherapy (SBRT) in Eclipse treatment planning system with the Normal tissue objective (NTO) tool sharp dose gradients beyond the target volume can be achived. NTO has 5 variable parameters, so it is difficult to know which settings are optimal. The purpose of this study was to characterize the effects of changing NTO parameters on lung SBRT dose distributions. Ten lung SBRT cases were replanned using different NTO parameters. Dose calculation was performed using AAA and AXB algorithms as well. Differences between AAA and AXB plans were statistically significant. Plans were evaluated based on plan quality metrics. According to this analysis the fall-off of 0.15 and the priority of 500 have satisfied our institutional criteria best. Using NTO during planning is recommended in clinical practice.</p>","PeriodicalId":18175,"journal":{"name":"Magyar onkologia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Magyar onkologia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/3/17 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

In treatment planning of small-sized lung tumors treated with stereotactic body radiotherapy (SBRT) in Eclipse treatment planning system with the Normal tissue objective (NTO) tool sharp dose gradients beyond the target volume can be achived. NTO has 5 variable parameters, so it is difficult to know which settings are optimal. The purpose of this study was to characterize the effects of changing NTO parameters on lung SBRT dose distributions. Ten lung SBRT cases were replanned using different NTO parameters. Dose calculation was performed using AAA and AXB algorithms as well. Differences between AAA and AXB plans were statistically significant. Plans were evaluated based on plan quality metrics. According to this analysis the fall-off of 0.15 and the priority of 500 have satisfied our institutional criteria best. Using NTO during planning is recommended in clinical practice.

分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
[正常组织客观参数对肺立体定向放疗剂量分布的影响]。
在Eclipse治疗计划系统中,使用正常组织物镜(NTO)工具进行立体定向放射治疗(SBRT)的小肺肿瘤的治疗计划时,可以实现超过靶体积的锐剂量梯度。NTO有5个可变参数,所以很难知道哪个设置是最优的。本研究的目的是表征改变NTO参数对肺SBRT剂量分布的影响。采用不同的NTO参数对10例肺SBRT进行重新规划。剂量计算采用AAA和AXB算法。AAA和AXB方案的差异有统计学意义。计划是基于计划质量度量来评估的。根据这一分析,0.15的下降和500的优先级最符合我们的制度标准。在临床实践中,建议在计划期间使用NTO。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Magyar onkologia
Magyar onkologia Medicine-Medicine (all)
CiteScore
0.60
自引率
0.00%
发文量
30
期刊最新文献
[The expanding possibilities of immuno-oncology treatments]. [Therapeutic drug monitoring for supporting oncological treatments: a new era begins]. [The role of classic serum tumor markers in the diagnosis and treatment monitoring of solid tumors in adults]. [Current therapeutic and familial implications of the genetic background of prostate cancer]. [Paraneoplastic endocrine syndromes: clinical picture and laboratory diagnostics].
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1