Intra- and extrauterine maturation of amplitude-integrated electroencephalographic activity in preterm infants younger than 30 weeks of gestation.

Biology of the neonate Pub Date : 2006-01-01 Epub Date: 2005-10-11 DOI:10.1159/000088912
Katrin Klebermass, Stefan Kuhle, Monika Olischar, Ernst Rücklinger, Arnold Pollak, Manfred Weninger
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引用次数: 58

Abstract

Objective: To prospectively investigate the longitudinal changes of amplitude-integrated electroencephalographic (aEEG) activity in preterm infants <30 weeks gestational age (GA).

Methods: Infants (GA <30 weeks) without evidence of neurological abnormalities had weekly aEEG recordings performed. The relative duration of the three aEEG patterns (discontinuous low voltage, discontinuous high voltage and continuous) was determined and the influence of GA and postnatal age (PNA) on the occurrence of each pattern was assessed.

Results: Ninety-eight infants (median GA 26 weeks; range 23-29 weeks) were studied. With higher GA (OR 1.68, 95% CI 1.33-2.13) and PNA (OR 1.91, 95% CI 1.53-2.38), the likelihood for the occurrence of continuous activity increased. The discontinuous low-voltage pattern was less likely to occur with increasing GA (OR 0.68, 95% CI 0.55-0.83) and PNA (OR 0.70, 95% CI 0.61-0.81).

Conclusion: Maturation of aEEG activity in preterm infants is influenced by both GA and PNA.

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小于妊娠30周的早产儿的振幅整合脑电图活动的宫内和宫外成熟。
目的:前瞻性研究早产儿波幅积分脑电图(aEEG)活动的纵向变化方法:婴儿(GA)结果:98例婴儿(GA中位数为26周;范围23-29周)。随着GA (OR 1.68, 95% CI 1.33-2.13)和PNA (OR 1.91, 95% CI 1.53-2.38)的增加,发生持续活动的可能性增加。随着GA (OR 0.68, 95% CI 0.55-0.83)和PNA (OR 0.70, 95% CI 0.61-0.81)的增加,不连续的低压模式发生的可能性降低。结论:GA和PNA共同影响早产儿aEEG活动的成熟。
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