[Comparison of the block characteristics of levobupivacaine vs bupivacaine for unilateral spinal block].

Rong-zong Liao, Jian-hong Peng, Yao-xiong Chen, Jin-yan Ou, Yu-ping Liang, Shu Zhou, Yu-wu Shi
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Abstract

Objective: To compare the block characteristics of levobupivacaine and bupivacaine for hypobaric unilateral spinal block.

Methods: Sixty patients undergoing hypobaric unilateral spinal block for lower extremity operations were randomized into 2 equal groups. In one group the patients were asked to lie on the uncompromised side for slow injection of hypobaric bupivacaine solution (0.75% 6 mg, diluted to 2 ml with distilled water) at the rate of 1 ml/15 s through a 27-gauge needle. The patients maintained their position for 15 min before shifting to a supine position. In the other group levobupivacaine was used instead.

Results: Statistical study showed that the block characteristics were of no significant difference between the 2 groups (P>0.05) except that the duration of motor block was shorter in levobupivacaine group than in bupivacaine group (P<0.05). Blood pressure or heart rate showed no significant difference between the two groups during operation.

Conclusion: The block characteristics of hypobaric unilateral spinal block with levobupivacaine or bupivacaine are similar and their effect on circulatory function is slight. Levobupivacaine provides an option in case bupivacaine is not available.

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[左旋布比卡因与布比卡因对单侧脊髓阻滞的阻滞特性比较]。
目的:比较左旋布比卡因与布比卡因在低压单侧脊髓阻滞中的阻滞特性。方法:60例行单侧低压脊髓阻滞下肢手术的患者随机分为2组。在一组中,患者被要求躺在未损伤的一侧,通过27号针以1 ml/15 s的速度缓慢注射低压布比卡因溶液(0.75% 6 mg,用蒸馏水稀释至2 ml)。患者保持体位15分钟后移至仰卧位。另一组用左布比卡因代替。结果:统计学研究显示,两组间除左旋布比卡因组运动阻滞持续时间短于布比卡因组外,阻滞特征无显著差异(P>0.05)。结论:左旋布比卡因与布比卡因对低压单侧脊髓阻滞阻滞的阻滞特征相似,对循环功能的影响较小。在没有布比卡因的情况下,左旋布比卡因提供了一种选择。
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