[Impact of a regional project on patterns of care for acute myocardial infarction].

Paolo Guastaroba, Pier Camillo Pavesi, Umberto Guiducci, Antonio Marzocchi, Aleardo Maresta, Roberto Grilli
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Abstract

Background: On May 2003 the Emilia-Romagna Regional Commission for Cardiology and Cardiac Surgery launched a project aimed at improving health service ability to adopt interventions of well-known effectiveness for the treatment of patients with acute myocardial infarction. One of the main goals was to stimulate the clinical and organizational responsibilities operating at the local level, in order to improve the frequency of use of primary percutaneous coronary intervention.

Methods: In assessing the overall impact of this regional project, an interrupted time series regression analysis was conducted, relying on information drawn from the regional hospital discharge database. Overall, 18 957 patients admitted for acute myocardial infarction during the period January 2001-June 2004 were considered.

Results: One year after the inception of the regional project, the estimate of its effect documented a statistically significant increase in the frequency of use of percutaneous coronary angioplasty (5.8%, 95% confidence interval 4.6%-6.9%), paralleled by an increase (3.2%, 95% confidence interval 1.14%-5.0%) in the number of those directly admitted to centers with interventional cardiology facilities. No effect was observed as for the proportion of patients admitted to highly specialized departments.

Conclusions: Despite the obvious limitations due both to source of information and study design, our findings document that the regional project had indeed some tangible impact, although variable across the different geographic areas of the region, on key aspects of the patterns of care of patients with acute myocardial infarction.

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[区域项目对急性心肌梗死护理模式的影响]。
背景:2003年5月,艾米利亚-罗马涅地区心脏病学和心脏外科委员会启动了一个项目,旨在提高保健服务能力,采用众所周知的有效干预措施治疗急性心肌梗死患者。其中一个主要目标是激发临床和组织在地方层面的责任,以提高经皮初级冠状动脉介入治疗的使用频率。方法:在评估该区域项目的总体影响时,采用中断时间序列回归分析方法,依赖于区域医院出院数据库的信息。在2001年1月至2004年6月期间,共纳入18957例急性心肌梗死患者。结果:在区域项目启动一年后,对其效果的估计表明,经皮冠状动脉成形术的使用频率在统计学上显著增加(5.8%,95%可信区间为4.6%-6.9%),与此同时,直接入住具有介入性心脏病学设施的中心的人数也增加了(3.2%,95%可信区间为1.14%-5.0%)。在高度专科住院的患者比例方面没有观察到任何影响。结论:尽管由于信息来源和研究设计存在明显的局限性,但我们的研究结果表明,该区域项目确实对急性心肌梗死患者护理模式的关键方面产生了一些切实的影响,尽管在该地区不同的地理区域存在差异。
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