Nuclear receptor regulation gears up another Notch.

Nuclear receptor signaling Pub Date : 2006-01-01 Epub Date: 2006-02-08 DOI:10.1621/nrs.04001
Borja Belandia, Malcolm G Parker
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引用次数: 9

Abstract

In this perspective we describe examples of crosstalk between nuclear receptors (NRs) and Notch signaling by means of direct functional interactions between components of both pathways. This crosstalk may provide eukaryotic organisms with molecular mechanisms for the coordination of llong-distance endocrine signals with cell-to-cell juxtacrine communication.

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核受体调节又启动了一个Notch。
从这个角度来看,我们描述了核受体(nr)和Notch信号之间的串扰的例子,通过两种途径的组成部分之间的直接功能相互作用。这种串扰可能为真核生物提供远距离内分泌信号与细胞间近距离通讯协调的分子机制。
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