Postoperative management of elective esophagectomy for cancer.

Rays Pub Date : 2005-10-01
Paola Aceto, Elisabetta Congedo, Alexander Cardone, Luca Zappia, Germano De Cosmo
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Abstract

Postoperative management after elective esophagectomy for cancer has not been standardized. Thoracoabdominal incision with associated pain, extended operative time with consequent extracellular fluid shifts, single lung ventilation, potential for prolonged postoperative mechanical ventilation and comorbidities in patients with esophageal cancer, all contribute to high perioperative risk. Respiratory problems remain the major cause of both mortality and morbidity after esophagectomy for cancer. A specific pulmonary disorder, acute respiratory distress syndrome (ARDS) occurs in 10-20% of patients after esophagectomy. ARDS mortality exceeds 50%. Atrial fibrillation, that complicates recovery in 20 to 25% of patients after esophagectomy, contributes to make outcome worse. Anesthesiologists should adopt strategies known to be able to optimize patient outcome. Decreased postoperative mortality and morbidity have been associated with epidural analgesia, bronchoscopy to clear persistent bronchial secretions, intraoperative fluid restriction and early extubation. It has been shown that setting up early respiratory physiotherapy and mobilitation may improve functional recovery.

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择期食管癌切除术的术后处理。
择期食管癌切除术后的术后管理尚未标准化。胸腹切口伴疼痛、手术时间延长伴细胞外液移位、单肺通气、术后机械通气时间延长的可能性以及食管癌患者的合并症都是围手术期高危因素。呼吸系统疾病仍然是食管癌切除术后死亡率和发病率的主要原因。一种特殊的肺部疾病,急性呼吸窘迫综合征(ARDS)发生在10-20%的食管切除术后患者中。ARDS死亡率超过50%。心房颤动使食管癌术后20% - 25%的患者恢复复杂化,使预后更糟。麻醉师应该采用已知的能够优化患者预后的策略。术后死亡率和发病率的降低与硬膜外镇痛、支气管镜检查清除持续性支气管分泌物、术中限制液体和早期拔管有关。已有研究表明,早期进行呼吸物理治疗和活动可以改善功能恢复。
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