Alcohol craving in outpatients with alcohol dependence: rate and clinical correlates.

Gihyun Yoon, Suck Won Kim, Paul Thuras, Jon E Grant, Joseph Westermeyer
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引用次数: 66

Abstract

Objective: The present study was undertaken to assess the rate and severity of alcohol craving symptoms among registered alcohol-dependent patients at a Veterans Affairs outpatient clinic. We also examined the relationship between alcohol craving and the clinical characteristics of alcohol-dependent patients.

Method: Participants included 101 alcohol-dependent veterans enrolled in an outpatient addiction clinic. Alcohol craving was measured by the Penn Alcohol Craving Scale. Alcoholism severity and clinical characteristics were assessed with the Addiction Severity Index, Timeline Followback method, and other instruments. Three alcohol-craving groups (low, moderate, and high) were identified and compared using their demographic and clinical characteristics. Multiple regression analysis was performed to evaluate the relationship between the potential predictors and alcohol craving.

Results: The rate of alcohol craving was as follows: low craving (46%), moderate craving (29%), and high craving (25%). When these three craving groups were compared using univariate analyses, patients with higher alcohol craving had significantly higher alcohol composite scores (last 30 days) and severe alcohol dependence (last 1 year). In multiple regression analysis, the model explained 50% of the variance in alcohol craving, with alcoholism severity (42%), withdrawal symptoms (5%), and depression (3%) as significant predictors.

Conclusions: Patients in an outpatient treatment setting had a wide range of alcohol cravings. Level of alcohol craving was directly associated with several increased indices of alcohol- and non-alcohol-related morbidity.

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酒精依赖门诊患者的酒精渴望:比率和临床相关性
目的:本研究旨在评估退伍军人事务部门诊登记的酒精依赖患者的酒精渴望症状的发生率和严重程度。我们还研究了酒精依赖患者的临床特征与酒精渴望之间的关系。方法:参与者包括101名在门诊成瘾诊所登记的酒精依赖退伍军人。对酒精的渴望是通过宾夕法尼亚酒精渴望量表来衡量的。使用成瘾严重程度指数、时间线回访法和其他工具评估酒精中毒严重程度和临床特征。三个酒精渴望组(低、中、高)被确定并使用他们的人口学和临床特征进行比较。进行多元回归分析以评估潜在预测因素与酒精渴望之间的关系。结果:对酒精的渴望率为:低渴望(46%),中等渴望(29%)和高渴望(25%)。当使用单变量分析比较这三个渴望组时,高酒精渴望患者的酒精综合评分(最近30天)和严重酒精依赖(最近1年)显着更高。在多元回归分析中,该模型解释了50%的酒精渴望差异,酒精中毒严重程度(42%),戒断症状(5%)和抑郁(3%)是重要的预测因素。结论:门诊患者对酒精的渴望范围很广。对酒精的渴望程度与酒精和非酒精相关发病率的几个指数增加直接相关。
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