Tuberculosis of male genital system--myth or reality in 21st century.

D Tzvetkov, P Tzvetkova
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引用次数: 15

Abstract

To review literature and our clinical experience with tuberculosis (TBC) of male genital tract. To analyze the localization of the specific process, association with other forms of TBC and its impact on fertility. The study comprises 69 male patients, average age 40.32 +/- 1.64 years who were diagnosed to have TBC of genital system. All laboratory, imaging, immunological and biological methods for detection of TBC were used as well as sperm count in patients with fertile problems. Time to set up of the diagnosis was 1 day to 19 years (median 26.82 +/- 6.76 months). TBC of the epididymis was found to be present in 78.26% of all cases. In 68.12%, unilateral affection was evident and involvement of left and right sites were similar. In 40.58% of patients, different grade of sperm quality alterations were diagnosed. Almost one-third of cases showed co-morbidity and 36.24% association with TBC of other organs and systems. TBC of male genital tract has a considerable impact on fertility and still remains a challenging medical problem. There is a growing body of evidence that regardless of all measures we should ring the bell about the possibility of a new widespread of TBC. Strong efforts are mandatory especially in developing countries and countries in transition like Eastern European Countries. Management of the disease should involve measures in health promotion programs, medical education health policy makers, and international cooperation.

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男性生殖系统结核病——21世纪的神话还是现实。
回顾男性生殖道结核(TBC)的文献和临床经验。分析其定位的具体过程、与其他形式TBC的关联及其对生育的影响。本研究纳入69例男性患者,平均年龄40.32±1.64岁,诊断为生殖系统TBC。所有用于检测TBC的实验室、影像学、免疫学和生物学方法以及生育问题患者的精子计数均被使用。确诊时间为1天至19年(中位26.82±6.76个月)。附睾TBC占所有病例的78.26%。68.12%的患者单侧病变明显,左右部位受累相似。40.58%的患者诊断出不同程度的精子质量改变。近三分之一的病例合并发病,36.24%的病例合并其他器官和系统的TBC。男性生殖道TBC对生育能力有相当大的影响,仍然是一个具有挑战性的医学问题。越来越多的证据表明,无论采取何种措施,我们都应该敲响警钟,提醒人们TBC有可能再次广泛传播。必须作出强有力的努力,特别是在发展中国家和东欧国家等转型期国家。疾病的管理应包括健康促进计划、医学教育、卫生政策制定者和国际合作等措施。
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