[Osteochondritis dissecans of the knee joint].

J P Petersen, J Steinhagen, P Catala-Lehnen, J Bruns
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引用次数: 2

Abstract

Osteochondritis dissecans is a disorder with a prevalence of 0.01 to 0.06 %. Men between 16 and 36 years of age are most commonly affected by it. In the western hemisphere, the knee is affected by this progressive disorder in 75 % of the cases, specifically the medial femoral condyle (70 - 80 %). The etiology is uncertain, although genetic defects, micro-trauma, ossification disorders and ischemia have been implicated. Pathogenetically, Osteochondritis dissecans is classified in four stages, whereas in stage one, there is merely a subchondrial edema. Without therapy this could lead to stage 4, with a free osteochondral joint fragment. Treatment is analogous with the stage of the disorder. Whereas conservative treatment may yield full recovery during stage 1, starting in stage 2, invasive treatment should be considered. When the cartilage surface remains intact retrograde procedures are indicated. If the cartilage is injured anterograde therapies, like the chondral or osteochondral transplantation, should be used.

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[膝关节夹层性骨软骨炎]。
夹层性骨软骨炎是一种患病率为0.01 ~ 0.06%的疾病。16至36岁的男性最常受其影响。在西半球,75%的病例膝关节受到这种进行性疾病的影响,特别是股骨内侧髁(70 - 80%)。病因不确定,虽然遗传缺陷,微创伤,骨化障碍和缺血已牵连。在病理上,剥离性骨软骨炎分为四个阶段,而在第一阶段,只有软骨下水肿。如果不进行治疗,这可能会导致第四阶段,出现游离的骨软骨关节碎片。治疗方法与疾病的阶段相似。保守治疗可在第1期完全恢复,但从第2期开始,应考虑有创治疗。当软骨表面保持完整时,建议行逆行手术。如果软骨受损,应采用顺行治疗,如软骨或骨软骨移植。
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