Current aspects of Shigella pathogenesis.

Alfredo G Torres
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Abstract

Bacillary dysentery (shigellosis) is a severe human disease caused by Shigellae. In recent years, a large amount of information has been generated regarding the host, pathogen and environmental factors that impact the pathogenesis of shigellosis at the cellular and molecular level. This review summarizes what is currently known about Shigella, detailing those factors that contribute to pathogenesis and examining the current progress in the development of a vaccine.

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志贺氏菌发病机制的现状。
细菌性痢疾(志贺氏菌病)是由志贺氏菌引起的一种严重的人类疾病。近年来,人们从细胞和分子水平上对影响志贺氏菌病发病的宿主、病原体和环境因素进行了大量的研究。本综述总结了目前对志贺氏菌的了解,详细介绍了导致发病的因素,并检查了目前疫苗开发的进展。
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