Magnetic field exposure and neurodegenerative diseases--recent epidemiological studies.

Kerstin Hug, Martin Röösli, Regula Rapp
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引用次数: 51

Abstract

Objectives: To analyse the results of recent studies not yet included in a 2003 report of the International Commission on Non-Ionizing Radiation Protection (ICNIRP) on occupational exposure to low-frequency electromagnetic fields as potential risk factor for neurodegenerative diseases.

Methods: A literature search was conducted in the online databases of PubMed, ISI Web of Knowledge, DIMDI and COCHRANE, as well as in specialised databases and journals. Eight studies published between January 2000 and July 2005 were included in the review.

Results: The findings of these studies contribute to the evidence of an association between occupational magnetic field exposure and the risk of dementia. Regarding amyotrophic lateral sclerosis, the recent results confirm earlier observations of an association with electric and electronic work and welding. Its relationship with magnetic field exposure remains unsolved. There are only few findings pointing towards an association between magnetic field exposure and Parkinson's disease.

Conclusions: The epidemiological evidence for an association between occupational exposure to low-frequency electromagnetic fields and the risk of dementia has increased during the last five years. The impact of potential confounders should be evaluated in further studies.

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磁场暴露与神经退行性疾病——最近的流行病学研究
目的:分析尚未列入国际非电离辐射防护委员会(ICNIRP) 2003年关于职业接触低频电磁场作为神经退行性疾病潜在危险因素的报告的近期研究结果。方法:在PubMed、ISI Web of Knowledge、DIMDI和COCHRANE等在线数据库以及专业数据库和期刊中进行文献检索。2000年1月至2005年7月期间发表的8项研究被纳入该综述。结果:这些研究的发现为职业磁场暴露与痴呆风险之间的关联提供了证据。关于肌萎缩性侧索硬化症,最近的研究结果证实了早期观察到的与电气和电子工作和焊接有关。其与磁场暴露的关系仍未得到解决。只有很少的研究结果指向磁场暴露和帕金森病之间的联系。结论:在过去五年中,职业暴露于低频电磁场与痴呆风险之间的关联的流行病学证据有所增加。潜在混杂因素的影响应在进一步的研究中进行评估。
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