[Quantitative evaluation of the focus range of juvenile onset recurrent respiratory papillomatosis].

Wenbin Lei, Zhenzhong Su, Weiping Wen, Liping Chai, Aiyun Jiang, Guangyu Luo, Jian Li
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Abstract

Objective: To investigate the clinical application of quantitative evaluation of the focus range of juvenile onset recurrent respiratory papillomatosis (JO-RRP).

Method: Disease severity was scored as the sum of ratings of 1 (minimal), 2 (moderate), or 3 (severe) for involvement of 22 areas of the respiratory tract and digestive tract. Sixty-eight cases with JO-RRP patients underwent 238 procedures were removed papillomas. A Storz laryngoscope was used to exposed and suspend the larynx, and an endoscope video system was used to display the pathological changes.

Result: The score of these cases range from 2 to 20, most of them range from 7 to 14. Papillomas were found in the larynx in each case, vocal cords and false vocal cords were the most common places involved. Nose, pharynx, hard palate, lung or esophagus involved was seldom found. The score declined as the patients underwent more procedures. It is in accord with the clinical characteristic of JO-RRP.

Conclusion: We concluded that our means of JO-RRP focus range quantitative evaluation could evaluate the severity and clinical curative effect objectively. It was a scientific and convenient way, and worth to be generalized.

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[少年起病复发性呼吸道乳头状瘤病病灶范围的定量评价]。
目的:探讨青少年复发性呼吸道乳头状瘤病(JO-RRP)病灶范围定量评价的临床应用。方法:疾病严重程度评分为1(轻微),2(中度)或3(严重),累及呼吸道和消化道的22个区域。68例JO-RRP患者经238次手术切除了乳头状瘤。采用Storz喉镜暴露悬吊喉部,内窥镜视频系统显示病理改变。结果:这些病例的得分在2 ~ 20分之间,大部分在7 ~ 14分之间。乳头状瘤均见于喉部,以声带和假声带为最常见受累部位。鼻部、咽部、硬腭、肺或食道很少受累。随着患者接受更多的手术,分数也会下降。符合JO-RRP的临床特点。结论:本文采用的JO-RRP焦点范围定量评价方法能客观评价病情严重程度和临床疗效。这是一种科学方便的方法,值得推广。
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