[In situ preservation of parathyroid glands in total or near total thyroidectomy].

Liying Yan, Suiqin Li, Shaoqiang Zhang, Yanxia Bai, Fang Quan, Ruimin Zhao
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Abstract

Objective: To investigate the preservation of parathyroid glands and its function during total or near-total thyroidectomy.

Method: One hundred and thirty one patients underwent total thyroidectomy, near total thyroidectomy, hemithyroidectomy and isthmectomy. In operation, the parathyroid glands were exposed, or were identified under microscope when necessary. The third rank of inferior thyroid arteries was ligated to preserve parathyroid glands in situ, and the parathyroid function was observed after thyroidectomy.

Result: Four patients (3%) had a transient hypoparathyroidism after thyroidectomy, 26 patients (20%) had a obviously biochemical hypocalcemia with no symptoms, 73 patients (56%) had a lower calcium level in the first 3 days after surgery compared with preoperative level, 28 (21%) patients who underwent ipsilateral total and contralateral subtotal isthmectomy were all normocalcemic after surgery. There were no permanent hypoparathyroidism and death in our study population.

Conclusion: In total or near-total thyroidectomy, parathyroid glands and its artery blood-supply should be exposed and preserved. Vasodilator and calcium supplementation should be given to patients with obviously lower serum calcium level after surgery to prevent permanent hypoparathyroidism.

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[全甲状腺或近全甲状腺切除术中甲状旁腺的原位保存]。
目的:探讨甲状旁腺在全甲状腺或近全甲状腺切除术中的保存及其功能。方法:131例患者行甲状腺全切、近全切、甲状腺切除术和峡部切除术。术中暴露甲状旁腺,必要时在显微镜下观察。结扎甲状腺下动脉第三行原位保留甲状旁腺,甲状腺切除术后观察甲状旁腺功能。结果:甲状腺切除术后出现一过性甲状旁腺功能减退4例(3%),无症状出现明显生化性低钙26例(20%),术后3 d钙水平较术前低73例(56%),同侧全胸廓和对侧次全胸廓切除术28例(21%)术后钙水平均正常。在我们的研究人群中没有永久性甲状旁腺功能减退和死亡。结论:在全甲状腺或近全甲状腺切除术中,应暴露并保留甲状旁腺及其动脉供血。术后血清钙水平明显降低的患者应给予血管扩张剂和补钙,以防止永久性甲状旁腺功能减退。
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