Obstructive sleep apnea: a palatable treatment option?

C Allison
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Abstract

(1) The Pillar(R) Palatal Implant System consists of three polyester threads that are permanently implanted in the palate (the roof of the mouth) to reduce airway obstruction in individuals with mild to moderate obstructive sleep apnea (OSA) and snoring. (2) Three small, non-randomized uncontrolled trials reported a moderate reduction in the number of breathing interruptions during sleep, three to six months following palatal implant insertion. Statistically significant improvements in daytime sleepiness and snoring intensity were also reported. (3) The minimally invasive surgical procedure causes mild, transient discomfort. A potential complication is partial extrusion of the implant, requiring removal and replacement. (4) Currently, there is insufficient published evidence to determine whether palatal implants are an effective treatment option for patients with mild to moderate OSA due to palatal obstruction. (5) Larger, randomized controlled studies are needed to determine the long-term safety and efficacy of the implants in a more diverse patient population, including those who are obese or those with comorbid medical conditions. Comparisons with existing treatments for OSA are also needed.

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阻塞性睡眠呼吸暂停:一种令人满意的治疗选择?
(1) Pillar(R) Palatal Implant System由三根永久植入上颚(上颚)的聚酯线组成,用于减轻轻度至中度阻塞性睡眠呼吸暂停(OSA)和打鼾患者的气道阻塞。(2)三个小型、非随机对照试验报告,在腭种植体植入后3至6个月,睡眠期间呼吸中断的次数适度减少。据统计,白天嗜睡和打鼾强度也有显著改善。(3)微创手术会引起轻微的、短暂的不适。潜在的并发症是种植体部分挤压,需要移除和更换。(4)目前,没有足够的公开证据来确定腭种植体是否是轻至中度腭梗阻OSA患者的有效治疗选择。(5)需要更大规模的随机对照研究来确定植入物在更多样化的患者群体中的长期安全性和有效性,包括那些肥胖或有合并症的患者。还需要与OSA的现有治疗方法进行比较。
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