HLA-A*68020103 shows an eight nucleotides deletion within intron 2 but has normal mRNA splicing and serological recognition.

A Balas, F Sánchez-García, L Bustamante, F García-Sánchez, J L Vicario
{"title":"HLA-A*68020103 shows an eight nucleotides deletion within intron 2 but has normal mRNA splicing and serological recognition.","authors":"A Balas,&nbsp;F Sánchez-García,&nbsp;L Bustamante,&nbsp;F García-Sánchez,&nbsp;J L Vicario","doi":"10.1111/j.1399-0039.2007.00874.x","DOIUrl":null,"url":null,"abstract":"<p><p>A novel A*68020103 allele was completely characterized by sequencing in a Spanish bone marrow donor. A*68020103 has an eight nucleotides deletion at the 5'-end of intron 2, when compared with other A*6802 alleles. This alteration does not affect either its mRNA splicing process or serological detection.</p>","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"70 3","pages":"258-9"},"PeriodicalIF":0.0000,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1399-0039.2007.00874.x","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tissue antigens","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/j.1399-0039.2007.00874.x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

Abstract

A novel A*68020103 allele was completely characterized by sequencing in a Spanish bone marrow donor. A*68020103 has an eight nucleotides deletion at the 5'-end of intron 2, when compared with other A*6802 alleles. This alteration does not affect either its mRNA splicing process or serological detection.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
HLA-A*68020103内含子2缺失8个核苷酸,但mRNA剪接正常,血清学识别正常。
一种新的A*68020103等位基因通过测序在西班牙骨髓供体中完全表征。与其他A*6802等位基因相比,A*68020103在内含子2的5'端缺失8个核苷酸。这种改变既不影响mRNA剪接过程,也不影响血清学检测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Tissue antigens
Tissue antigens 医学-病理学
自引率
0.00%
发文量
0
审稿时长
6 months
期刊最新文献
Identification of a novel HLA-DRB1*14 allele, HLA-DRB1*14:143, by sequence-based typing. Identification of the novel HLA-A allele, HLA-A*24:96, in a Chinese individual. CCR5 gene polymorphism is a genetic risk factor for radiographic severity of rheumatoid arthritis. A HLA-A null allele (A*24:132N) with a stop codon in exon 3 generated by a point mutation. Detection of complement-fixing and non-fixing antibodies specific for endothelial precursor cells and lymphocytes using flow cytometry.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1