{"title":"Metabolism of deltamethrin in rats.","authors":"S El-Maghraby","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To study the metabolism of 14C-deltamethrin in rats.</p><p><strong>Methods: </strong>Rats were dosed orally and i.p. with a single dose of 14C-deltamethrin (0.64 mg/Kg) body weight. The required dose was applied daily for 3 days. At the end of the experiment, selected organs, such as liver, kidney, fat, intestine, and blood were excised for radioassay of 14C-content.</p><p><strong>Results: </strong>Deltamethrin was almost eliminated from the body within 1-3 days. The main portion of 14C-residues was extracted from urine (38%, 32%) and feces (20%, 24%) with a little amount remained in various organs.</p><p><strong>Conclusion: </strong>The elimination and distribution of 14C-radioactivity in rats treated orally and intraperitoneally signify that deltamethrin is bioavailable in urine and feces.</p>","PeriodicalId":9108,"journal":{"name":"Biomedical and environmental sciences : BES","volume":"20 3","pages":"212-6"},"PeriodicalIF":0.0000,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical and environmental sciences : BES","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: To study the metabolism of 14C-deltamethrin in rats.
Methods: Rats were dosed orally and i.p. with a single dose of 14C-deltamethrin (0.64 mg/Kg) body weight. The required dose was applied daily for 3 days. At the end of the experiment, selected organs, such as liver, kidney, fat, intestine, and blood were excised for radioassay of 14C-content.
Results: Deltamethrin was almost eliminated from the body within 1-3 days. The main portion of 14C-residues was extracted from urine (38%, 32%) and feces (20%, 24%) with a little amount remained in various organs.
Conclusion: The elimination and distribution of 14C-radioactivity in rats treated orally and intraperitoneally signify that deltamethrin is bioavailable in urine and feces.
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
