Use of pulse transit time as a measure of autonomic arousals in patients with obstructive sleep apnea.

Yi Xiao, Xu Zhong, Rong Huang
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Abstract

Objective: To evaluate the feasibility of pulse transit time (PTT) arousals as an index of sleep fragmentation in patients with obstructive sleep apnea hypopnea syndrome (OSAHS).

Methods: Individuals referred for evaluation of possible OSAHS underwent overnight polysomnography (PSG). Three conventional indices of sleep fragmentation [electroencephalography (EEG) arousals, apnea/hypopnea index (AHI) , oxygen desaturation index (ODI)] , PTT arousals, and Epworth sleepiness scale (ESS) were compared.

Results: PTT arousals were positively correlated with EEG arousals (r = 0.746, P < 0.001), AHI (r = 0.786, P < 0.001), and ODI (r = 0.665, P < 0.001) , respectively. But, both PTT arousals and EEG arousals had no correlation with ESS (r = 0.432, P = 0.201; r = 0.196, P = 0.591, respectively).

Conclusion: PTT arousals are correlated well with other standard measures estimating severity of OSAHS and potentially a non-invasive marker with which to measure the sleep fragmentation in patients with OSAHS.

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使用脉冲传递时间测量阻塞性睡眠呼吸暂停患者的自主觉醒。
目的:评价脉冲传递时间(PTT)唤醒作为阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者睡眠片段化指标的可行性。方法:对疑似OSAHS患者进行夜间多导睡眠描记(PSG)检查。比较3项常规睡眠碎片化指标[脑电图(EEG)唤醒次数、呼吸暂停/低通气指数(AHI)、氧去饱和指数(ODI)]、PTT唤醒次数和Epworth嗜睡量表(ESS)。结果:PTT觉醒与EEG觉醒(r = 0.746, P < 0.001)、AHI (r = 0.786, P < 0.001)、ODI (r = 0.665, P < 0.001)呈正相关。但PTT唤醒和EEG唤醒与ESS无相关性(r = 0.432, P = 0.201;r = 0.196, P = 0.591)。结论:PTT唤醒与其他评价OSAHS严重程度的标准测量具有良好的相关性,可能是衡量OSAHS患者睡眠破碎性的无创指标。
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