Use of fetal fibronectin in the management of preterm labour in Nunavut.

Alaska medicine Pub Date : 2007-01-01
W A MacDonald, M Bender, A Saxton
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Abstract

Objectives: To manage suspected preterm labour in the Baffin Region of Nunavut safely and more conservatively utilizing the Fetal Fibronectin Assay.

Study design: Chart Review.

Methods: The trial of Fetal Fibronectin took place in the Baffin Region of Nunavut. An initial chart review of all admissions for "false labour" to Baffin Regional Hospital was performed. An analysis of the cases was done to determine when the women delivered and whether they had been Medevaced. The Fetal Fibronectin test was implemented at five sites in the Baffin Region and data on each use of the assay were collected by the laboratory at Baffin Regional Hospital. A review of the data for the first 13 months of the trial was then done.

Results: The test was used 38 times between July 2004 and September 2005. There were 31 negative results. Most of the cases with negative results were managed conservatively, with a total of 18 Medevacs avoided. There were no false negative tests. Cost savings for avoided Medevacs were in the order of $200,000.

Conclusions: The Fetal Fibronectin Assay has proven to be a valuable adjunct in the management of suspected preterm labour in Nunavut.

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胎儿纤维连接蛋白在努勒维特地区早产管理中的应用。
目的:利用胎儿纤维连接蛋白测定法安全、保守地处理努勒维特巴芬地区的疑似早产。研究设计:图表回顾。方法:在努纳武特巴芬地区进行胎儿纤维连接蛋白试验。对所有到巴芬地区医院就诊的"假分娩"进行了初步的图表审查。对这些病例进行了分析,以确定这些妇女分娩的时间以及她们是否接受了医疗器械治疗。胎儿纤维连接蛋白试验在巴芬地区的五个地点实施,每次使用该试验的数据由巴芬地区医院的实验室收集。然后对试验前13个月的数据进行了回顾。结果:2004年7月~ 2005年9月共使用38次。阴性结果31例。多数阴性病例均采取保守处理,共避免18次医疗后送。没有假阴性测试避免使用医疗后送机节省的费用约为20万美元。结论:胎儿纤维连接蛋白测定已被证明是一个有价值的辅助管理疑似早产在努纳武特。
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