An optical fiber photoplethysmographic system for central nervous system tissue.

Justin P Phillips, Panayiotis A Kyriacou, Kuriakose J George, John V Priestley, Richard M Langford
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引用次数: 11

Abstract

A new system for measuring the oxygen saturation of blood within tissue has been developed, for a number of potential patient monitoring applications. This proof of concept project aims to address the unmet need of real-time measurement of oxygen saturation in the central nervous system (CNS) for patients recovering from neurosurgery or trauma, by developing a fiber optic signal acquisition system for internal placement through small apertures. The development and testing of a two-wavelength optical fiber reflectance photoplethysmography (PPG) system is described. It was found that good quality red and near-infrared PPG signals could be consistently obtained from the human fingertip (n=6) and rat spinal cord (n=6) using the fiber optic probe. These findings justify further development and clinical evaluation of this fiber optic system.

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一种用于中枢神经系统组织的光纤光体积描记系统。
一种用于测量组织内血液氧饱和度的新系统已经开发出来,用于许多潜在的患者监测应用。该概念验证项目旨在通过开发一种通过小孔径内部放置的光纤信号采集系统,解决神经外科手术或创伤恢复患者对中枢神经系统(CNS)氧饱和度实时测量的未满足需求。介绍了一种双波长光纤反射光体积脉搏波(PPG)系统的研制与测试。研究发现,利用光纤探针可以从人的指尖(n=6)和大鼠的脊髓(n=6)连续获得高质量的红色和近红外PPG信号。这些发现证明了该光纤系统的进一步发展和临床评价。
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